| 五田保肝颗粒的提取工艺研究 |
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| 引用本文： | 黄美菊,刘佩莉,孔令钰,陈灵芝,李楠,毕业东,王倩. 五田保肝颗粒的提取工艺研究[J]. 天津中医药大学学报, 2013, 30(9): 564-566 |
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| 作者姓名： | 黄美菊 刘佩莉 孔令钰 陈灵芝 李楠 毕业东 王倩 |
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| 作者单位： | 天津中医药大学, 天津 300193;天津市医药科学研究所药代动力学室, 天津 300020;天津市医药科学研究所药代动力学室, 天津 300020;天津中医药大学, 天津 300193;天津市医药科学研究所药代动力学室, 天津 300020;天津市汉沽区中医医院, 天津 300480;天津市医药科学研究所药代动力学室, 天津 300020 |
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| 基金项目： | 天津市中医药管理局中医中西医结合科研课题资助项目(11084) |
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| 摘 要： | [目的] 优化五田保肝颗粒的提取工艺。[方法] 采用正交实验设计,以干膏得率、总黄酮含量和五味子醇甲含量为评定指标,通过多指标综合评分优选五田保肝颗粒的提取工艺。[结果] 最佳提取工艺条件为12倍量40%乙醇提取3次,每次2 h。[结论] 所确定的最佳提取工艺合理,有效成分提取效率高。
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| 关 键 词： | 五田保肝颗粒 正交实验 综合评分法 |
| 收稿时间： | 2013-05-05 |
Study on the extracting procedure of Wutian Baogan granules |
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| HUANG Mei-ju,LIU Pei-li,KONG Ling-yu,CHEN Ling-zhi,LI Nan,BI Ye-dong and WANG Qian. Study on the extracting procedure of Wutian Baogan granules[J]. Journal of Tianjin University of Traditonal Chinese Medicine, 2013, 30(9): 564-566 |
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| Authors: | HUANG Mei-ju LIU Pei-li KONG Ling-yu CHEN Ling-zhi LI Nan BI Ye-dong WANG Qian |
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| Affiliation: | Tianjin University of TCM, Tianjin 300193, China;Pharmacokinetics Department of Tianjin Institute of Medical and Pharmaceutical Science, Tianjin 300020, China;Pharmacokinetics Department of Tianjin Institute of Medical and Pharmaceutical Science, Tianjin 300020, China;Tianjin University of TCM, Tianjin 300193, China;Pharmacokinetics Department of Tianjin Institute of Medical and Pharmaceutical Science, Tianjin 300020, China;Hangu Hospital of Traditional Chinese Medicine, Tianjin 300480, China;Pharmacokinetics Department of Tianjin Institute of Medical and Pharmaceutical Science, Tianjin 300020, China |
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| Abstract: | [Objective] To optimize the extraction process for Wutian Baogan granules.[Methods] The orthogonal test was employed and taking the extraction rate and the content of flavonoids and schisandrinas the index,using comprehensive evaluation score the extraction process of Wutian Baogan granules was optimized.[Results] The optimal extraction technique conditions were as follows: 12 times of amount of 40% ethanol, extracted for 3 times, each time for 2 hours.[Conclusion] The optimized extraction technology is rational and the extraction rate of the active ingredients is high. |
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| Keywords: | Wutian Baogan granule orthogonal test comprehensive evaluation method |
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