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Rapid reduction in BCR‐ABL1 transcript predicts deep molecular response in dasatinib‐treated chronic‐phase chronic myeloid leukaemia patients
Authors:Kazunori Murai  Kohei Yamaguchi  Shigeki Ito  Takuto Miyagishima  Motohiro Shindo  Kentaro Wakasa  Mitsue Inomata  Takahiro Nagashima  Takeshi Kondo  Nozomu Fujimoto  Satoshi Yamamoto  Masakatsu Yonezumi  Tatsuo Oyake  Shugo Kowata  Yasuhiko Tsukushi  Takahiro Mine  Kuniaki Meguro  Kazuhiko Ikeda  Reiko Watanabe  Souichi Saito  Shinji Sato  Katsushi Tajima  Takaaki Chou  Kohmei Kubo  Koji Oba  Junichi Sakamoto  Yoji Ishida  The Inter‐Michinoku Dasatinib Study Group
Affiliation:1. Division of Hematology and Oncology, Department of Internal Medicine, Iwate Medical University School of Medicine, Morioka, Japan;2. Department of Hematology, Iwate Prefectural Central Hospital, Morioka, Japan;3. Department of Hematology, Aomori Prefectural Central Hospital, Aomori, Japan;4. Department of Clinical Oncology, School of Medicine, Iwate Medical University, Morioka, Japan;5. Department of Internal Medicine, Japan Labour Health and Welfare Organization, Kushiro Rosai Hospital, Kushiro, Japan;6. Division of Gastroenterology and Hematology/Oncology, Asahikawa Medical University, Asahikawa, Japan;7. Division of Hematology, Hokkaido P.W.F.A.C. Obihiro‐Kosei General Hospital, Obihiro, Japan;8. Division of Hematology, National Hospital Organization Sendai Medical Center, Sendai, Japan;9. Department of Internal Medicine, Kitami Red Cross Hospital, Kitami, Japan;10. Department of Hematology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan;11. Division of Hematology, Kaisei Hospital, Sapporo, Japan;12. Department of Hematology, Sapporo City General Hospital, Sapporo, Japan;13. Department of Hematology, Hokkaido Cancer Center, Sapporo, Japan;14. Department of Cardiology and Hematology, Fukushima Medical University, Fukushima, Japan;15. Department of Hematology, Saitama Medical Center, Saitama Medical University, Kawagoe, Japan;16. Department of Internal Medicine, Nihonkai General Hospital, Sakata, Japan;17. Department of Hematology, Okitama Public General Hospital, Kawanishimachi Higashi Okitama‐gun, Japan;18. Department of Neurology, Hematology, Metabolism, and Diabetology (DNHMED), Yamagata University Faculty of Medicine, Yamagata, Japan;19. Department of Internal Medicine, Niigata Cancer Center Hospital, Niigata, Japan;20. Department of Biostatistics, School of Public Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan;21. Interfaculty Initiative in Information Studies, The University of Tokyo, Tokyo, Japan;22. Tokai Central Hospital, Kakamigahara, Japan
Abstract:
Keywords:chronic myeloid leukaemia  deep molecular response  tyrosine kinase inhibitors
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