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The cellular transfer of immunity to Trichostrongylus colubriformis in an isogenic strain of guinea-pig: IV. The localization of immune lymphocytes in small intestine in infected and non-infected guinea-pigs
Authors:J. K. Dineen   P. M. Ronai     B. M. Wagland
Abstract:Immune and non-immune mesenteric lymph node and Peyer's patch cells were labelled in vitro with 51Cr and injected intravenously into infected and non-infected syngeneic guinea-pigs (Heston strain). From the distribution of the radioactive label in the small intestine (the site of infection of T. colubriformis) it was concluded that immune lymphocytes: (1) preferentially localize or `home in' on the infection, (2) come into intimate contact with the parasite in the epithelium, and (3) rapidly undergo `allergic death' or lysis at the site of infection.
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