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微视野计对糖尿病性黄斑水肿患者的视功能评估
引用本文:李红 宋艳萍. 微视野计对糖尿病性黄斑水肿患者的视功能评估[J]. 眼科, 2021, 30(3): 236-239. DOI: 10.13281/j.cnki.issn.1004-4469.2021.03.014
作者姓名:李红 宋艳萍
作者单位:1.西安爱尔眼科医院 710061;2解放军武汉总医院,武汉430070
基金项目:国家自然科学基金(61378084)
摘    要:目的 采用微视野检测对糖尿病性黄斑水肿(DME)患者视功能进行评估,并探讨微视野检测指标与视力之间的相关性.设计 回顾性病例系列.研究对象 2016年4月至2018年1月在中国人民解放军武汉总医院确诊为DME的患者164例(220眼).方法 患者均行最佳矫正视力(BCVA)检查(统计时结果转换为最小分辨角对数(logM...

关 键 词:糖尿病性黄斑水肿  微视野  固视率
收稿时间:2018-02-11

Evalution of the macular function by microperimetry in dabetic macular edema
Li Hong,Song Yanping. Evalution of the macular function by microperimetry in dabetic macular edema[J]. Ophthalmology in China, 2021, 30(3): 236-239. DOI: 10.13281/j.cnki.issn.1004-4469.2021.03.014
Authors:Li Hong  Song Yanping
Affiliation:1 Xi’an Aier Eye Hospital, Xi’an 710061, China; 2Wuhan General Hospital of Chinese People's Liberation Army, Wuhan 430070, China
Abstract:Objective To evaluate the visual function of diabetic macular edema (DME) patients by microperimetry, and evaluate the association of microperimetry measurements and visual acuity. Design Retrospective case series. Participants 220 eyes of 164 patients with DME were enrolled in Wuhan General Hospital of Chinese People's Liberation Army from April 2016 to January 2018. Methods All patients were examined with best corrected visual acuity (BCVA, logMAR), fluorescein fundus angiography (FFA), optical coherence tomography(OCT), full retinoscoppy, MAIA microperimetry. According to the fixation rate, the subjects were divided into 3 groups:stable fixation,relative unstable fixation, and unstable fixation. According to the difference of retinal sensitivity, 3 stages of fixation stability were divided: A1 (normal), A2 (suspicious), and A3 (abnormal), and the visual acuity of different retinal sensitivity groups in the fixation group were compared. Main outcome measures BCVA, average threshold (AT), 2 degree fixation rate (P1), 4 degree fixation rate (P2) and bivariate contour ellipse area for 63% (BCEA63), BCEA95. Results In patients with DME, the AT of stable group, relatively unstable group and unstable group was 23.55±3.90 dB, 20.87±6.04 dB, 19.30±5.41 dB, respectively (F=9.824,P=0.00). The BCVA (logMAR) of stable group, relatively unstable group and unstable group was 0.38±0.24, 0.59±0.29, 0.63±0.31, respectively (F=9.808,P=0.000). In the stable group, the BCVA of A1, A2 and A3 groups were 0.22±0.15, 0.36±0.21, 0.51±0.24, respectively (F=16.14, P<0.001). In the patients of DME, logMAR BCVA was negatively correlated with AT(r=-0.712,P=0.000)、P1(r=-0.380,P=0.000)、P2 (r=-0.370,P=0.000), and positively correlated with BCEA 63 (r=0.352, P=0.000), and BCEA95 (r=0.355, P=0.000). Multiple linear regression analysis showed that logMAR BCVA was independently affected by AT (OR=0.576,P=0.000) and P1(OR=0.800,P=0.000). Conclusion MAIA microperimetry can assess macular visual function in patients with DME. AT and P1 can be used as a good indicator for the evaluation of macular visual function and a predictor of logMAR BCVA. It can reflect the visual function of patients with DME. (Ophthalmol CHN, 2021, 30: 236-239)
Keywords:dabetic macular edema   microperimetry   fixation rate  
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