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女童膳食模式与中枢性性早熟的关联
引用本文:袁静怡,张功,王亚,江伟康,刘婉旭,徐玉祥,孙莹. 女童膳食模式与中枢性性早熟的关联[J]. 中国学校卫生, 2021, 42(5): 737-741. DOI: 10.16835/j.cnki.1000-9817.2021.05.023
作者姓名:袁静怡  张功  王亚  江伟康  刘婉旭  徐玉祥  孙莹
作者单位:1.安徽医科大学公共卫生学院儿少卫生与妇幼保健学系/人口健康与优生安徽重点实验室,合肥 230032
基金项目:国家自然科学基金81872638安徽省自然基金杰青项目1908085J26安徽省卫生健康委科研项目AHWJ2021b101
摘    要:目的 探讨儿童膳食模式与中枢性性早熟的关联,为性早熟的饮食预防提供科学依据.方法 采用病例对照研究方法,选取2019年5-12月在安徽省合肥市某医院初诊为中枢性性早熟的35名女童为病例组,70名青春期发育正常的健康女童为对照组,开展体格发育检查、父母问卷调查和儿童访谈.饮食评估采用简化的食物频率问卷(Food Freq...

关 键 词:饮食习惯  青春期,早熟  生长和发育  回归分析  儿童
收稿时间:2020-08-27

Association between dietary patterns and central precocious puberty in girls
Affiliation:1.Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei(230032), China
Abstract:  Objective  To explore the relationship between dietary patterns and central precocious puberty in children, and to provide a scientific basis for dietary prevention of precocious puberty.  Methods  A case-control study was conducted, among 35 newly diagnosed central precocious puberty girls from May to December 2019 as the case group, and 70 healthy girls with normal development as the control group. Physical development examination, parent questionnaire survey and child interview were carried out. Dietary information was assessed using a simplified food frequency questionnaire(FFQ). Principal component analysis was used to identify children's dietary patterns, and multiple Logistic regression was used to assess the association between dietary patterns and precocious puberty.  Results  Three different dietary patterns have been established, namely "snack and processed food type", "animal protein type" and "nutritional tonic type" dietary patterns, respectively. After adjusting for covariates such as age and BMI, Logistic regression analysis showed that the "snack and processed food type" dietary pattern was positively correlated with precocious puberty(OR=10.81, 95%CI=2.59-45.15, P < 0.01). There was a negative correlation between "animal protein type" and precocious puberty(OR=0.24, 95%CI=0.06-0.91, P=0.04), while the association between "nutritive tonic" and precocious puberty was not statistically significant(OR=0.28, 95%CI=0.07-1.05, P=0.06).  Conclusion  Children's dietary patterns were related to precocious puberty." Snack and processed food "dietary pattern with a high intake of fried foods, puffed foods, foods containing preservatives or pigments, western fast foods, chocolate and products, was closely related to central precocious puberty.
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