| 慢性阻塞性肺疾病与冠状动脉疾病之间的双向关系 |
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| 引用本文： | 赵伟豪,步睿,王晓云. 慢性阻塞性肺疾病与冠状动脉疾病之间的双向关系[J]. 心脏杂志, 2021, 33(1): 92-94,100. DOI: 10.12125/j.chj.202003095 |
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| 作者姓名： | 赵伟豪 步睿 王晓云 |
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| 作者单位： | 哈尔滨医科大学附属第四医院心血管内科，黑龙江 哈尔滨 150001 |
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| 基金项目： | 国家自然科学基金项目资助(61572152) |
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| 摘 要： | 慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)与冠状动脉疾病(coronary artery disease,CAD)不仅有吸烟这一相同的危险因素,而且还具有流行病学关系.有充分的证据表明在CAD患者中发生COPD十分普遍,但常被漏诊,反之亦然.这两种疾病的晚期...
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| 关 键 词： | 慢性阻塞性肺疾病 冠状动脉疾病 动脉粥样硬化 发病率 炎症 |
| 收稿时间： | 2020-03-25 |
Bidirectional relationship between chronic obstructive pulmonary disease and coronary artery disease |
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| Affiliation: | Department of Cardiology, Fourth Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang, China |
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| Abstract: | Chronic obstructive pulmonary disease (COPD) and coronary artery disease (CAD) not only have smoking as a common risk factor, they also share epidemiological relationships. There is good evidence to suggest that COPD is highly prevalent but under-diagnosed in CAD patients and vice versa. The symptoms of the two diseases can overlap, making differential diagnosis difficult. This highlights the importance of pulmonary function tests (PFTs) in patients with CAD, which is also a cardiological assessment in patients with COPD. COPD is a risk factor for the development of CAD independent of other cardiovascular risk factors and the presence of COPD worsens the prognosis in patients with CAD. Mechanisms underlying the associations between COPD and CAD have been less well studied, but inflammation is increasingly being recognized as an important factor linking the two diseases. Other potential contributors include increased oxidative stress, platelet activation and arterial stiffness. Physicians need to be aware of the important links between COPD and CAD, which helps to optimize the management of both conditions and improve patient outcomes. |
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