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Severe Stevens‐Johnson syndrome/toxic epidermal necrolysis overlap syndrome—beyond skin involvement
Authors:Tiago Milheiro Silva MD  João Farela Neves MD  Ana Casimiro MD  Luís Varandas PhD  Catarina Gouveia MD
Affiliation:Centro Hospitalar de Lisboa Central–EPE, Hospital Dona Estefania, Lisbon, Portugal
Abstract:Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but serious dermatologic diseases with many potential multisystem complications. We describe the case of an 8‐year‐old girl who developed severe SJS/TEN overlap syndrome (25% of her body surface area was affected) complicated by pancreatitis and bronchiolitis obliterans. These rare complications emphasize the need for careful, intensive monitoring of possible complications and an interdisciplinary team approach to provide optimal treatment and follow‐up.
Keywords:drug reaction  mucous membrane disorders  pharmacology  skin barrier
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