| 2017年北京市昌平区健康人群麻疹抗体水平监测结果分析 |
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| 引用本文： | 王涛,王海红,易文娟,苑新海,朱宗龙,杨俊英. 2017年北京市昌平区健康人群麻疹抗体水平监测结果分析[J]. 疾病监测, 2018, 33(9): 728-731. DOI: 10.3784/j.issn.1003-9961.2018.09.007 |
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| 作者姓名： | 王涛 王海红 易文娟 苑新海 朱宗龙 杨俊英 |
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| 作者单位： | 北京市昌平区疾病预防控制中心，北京 102200 |
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| 摘 要： | 目的了解北京市昌平区健康人群麻疹抗体水平，及时发现免疫薄弱人群及疾病传播流行存在的隐患，为制订消除麻疹策略与措施提供科学依据。方法采取单纯随机抽样方法采集360名健康人群的血标本，采用酶联免疫吸附试验检测血清麻疹IgG抗体，分析抗体阳性率和抗体几何平均滴度（GMC）。结果昌平区健康人群麻疹抗体阳性率为82.22%，GMC达1 109.59 mIU/ml。 1 ~ 4岁与5 ~ 9岁年龄组GMC差异无统计学意义（F＝0.734，P＞0.05）。 不同性别、户籍和免疫剂次人群间麻疹抗体阳性率和GMC均差异无统计学意义。 接种含麻疹成分疫苗（MCV）后，＜1、1 ~ 4、5 ~ 8岁年龄组麻疹抗体阳性率和GMC均差异无统计学意义。结论昌平区麻疹抗体阳性率处于较高水平，需加强本市成年人及重点年龄组人群，尤其是大学生的MCV接种工作。
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| 关 键 词： | 健康人群 麻疹 抗体 |
| 收稿时间： | 2017-12-27 |
Surveillance for measles antibody level in healthy population in Changping district of Beijing, 2017 |
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| Affiliation: | Changping District Center for Disease Control and Prevention, Beijing 102200, China |
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| Abstract: | ObjectiveTo understand the measles antibody level in healthy population in Changping district of Beijing, discover the susceptible population and disease spread risk, and provide scientific evidence for measles elimination strategies.MethodsBlood samples were collected from 300 healthy persons selected through simple random sampling in Changping for the detection of serum IgG against measles virus with enzyme linked immunosorbent assay (ELISA).ResultsThe measles antibody positive rate was 82.22% in healthy population in Changping, and the geometric mean concentration (GMC) of the antibody was 1 109.59 mIU/ml. The difference in GMC was not significant between age group 1–4 years and age group 5–9 years (F＝0.734, P＞0.05). The differences in measles antibody positive rate and GMC between males and females and among the people with different household registration status and doses of measles vaccination had no significance. After the immunization of measles-containing vaccine (MCV), the differences in measles antibody positive rate and GMC among age groups ＜1 year, 1–4 years and 5–8 years were not significant.ConclusionThe positive rate of measles antibody was at high level in healthy population in Changping, but it is still necessary to strengthen the MCV immunization in adults and other age groups at risk, especially in college students. |
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