| 初治肺结核患者门诊发现并发肺部其他感染的临床特点 |
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| 引用本文： | 谭守勇,龚芳,刘国标,黎燕琼. 初治肺结核患者门诊发现并发肺部其他感染的临床特点[J]. 中国防痨杂志, 2018, 40(9): 944-947. DOI: 10.3969/j.issn.1000-6621.2018.09.007 |
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| 作者姓名： | 谭守勇 龚芳 刘国标 黎燕琼 |
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| 作者单位： | 1. 510095 广州市胸科医院 国家呼吸疾病重点实验室;2. 广州市结核病防治所一分所 |
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| 基金项目： | 广州市科技计划项目(155700012);广州市科技计划项目/健康医疗协同创新重大专项(201508020248) |
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| 摘 要： | 目的 了解结核专科门诊发现初治肺结核患者并发肺部其他感染现状,探讨肺结核并发肺部其他感染患者的临床特点。方法 回顾性分析2015年1月至2016年6月在广州市结核病防治所一分所就诊的、临床资料完整的初治菌阳肺结核患者506例,根据患者就诊时是否并发肺部其他感染,分为肺结核并发肺部其他感染组(简称“并发感染组”;共计200例)及肺结核未并发其他感染组(简称“对照组”;共计306例)。506例患者中有98例为老年患者。应用SPSS 19.0软件进行统计学分析,计数资料采用χ 2检验,以P<0.05为差异有统计学意义。 结果 (1)并发感染组200例,占39.53%;在并发感染组中,老年患者比例(24.50%,49/200)明显高于对照组(16.01%,49/306)(χ 2=6.583,P=0.037),两组比较差异有统计学意义;(2)在并发感染组中,伴有咳嗽或咳痰症状者占83.00%(166/200),与对照组的76.47%(234/306)相似,两组比较差异无统计学意义(χ 2=3.510,P=0.319);(3)并发感染组肺部累及病灶>3个肺野者占49.00%(98/200),明显高于对照组的31.70%(97/306),两组比较差异有统计学意义(χ 2=6.965,P=0.008);(4)并发感染组患者中,肺结核并发空洞者占42.50%(85/200),明显高于对照组的26.80%(82/306),两组比较差异有统计学意义(χ 2=13.487,P=0.000)。 结论 结核专科门诊发现初治菌阳肺结核并发肺部其他感染患者中,老年患者并发肺部其他感染的比例较高,并发感染组患者肺部病灶累及范围较广泛,常伴有空洞形成。
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| 关 键 词： | 结核 肺 重叠感染 门诊病人 对比研究 |
| 收稿时间： | 2018-02-02 |
Clinical characteristics of new pulmonary tuberculosis cases complicated with pulmonary other infection in tuberculosis clinic |
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| Shou-yong TAN,Fang GONG,Guo-biao LIU,Yan-qiong LI. Clinical characteristics of new pulmonary tuberculosis cases complicated with pulmonary other infection in tuberculosis clinic[J]. The Journal of The Chinese Antituberculosis Association, 2018, 40(9): 944-947. DOI: 10.3969/j.issn.1000-6621.2018.09.007 |
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| Authors: | Shou-yong TAN Fang GONG Guo-biao LIU Yan-qiong LI |
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| Affiliation: | 1. State Key Laboratory of Respiratory Diseases,Guangzhou Chest Hospital,Guangzhou 510095,China |
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| Abstract: | Objective To understand the present situation of the pulmonary tuberculosis cases with pulmonary other infection (PTB&PIN), and to explore the patients’ clinical characteristics for PTB&PIN in TB clinic.Methods A retrospective analysis was carried out on 506 new bacteriological positive PTB patients with the complete clinical data from January 2015 to June 2016 in a TB prevention and treatment center in Yuexiu district of Guangzhou. The patients were divided into the infection group (n=200) and the control group (n=306), according to whether they had complicated pulmonary infection or not at the time of visit. SPSS 19.0 software was used for statistical analysis, the counting data were analyzed by Chi-square test, which was statistical significance with P<0.05.Results (1) Of the 506 patients with PTB, 200 cases (39.53%) were complicated with PIN. There were 24.50% (49/200) patients aged over 60 years in the infection group, which was significantly higher than that in the control group (16.01%, 49/306) (χ 2=6.583, P=0.037). (2) In the infection group, there were 83.00% (166/200) patients with cough or expectoration symptoms, which was same as 76.47% (234/306)(χ 2=3.510, P=0.319) in the control group. (3) And there were 49.00% (98/200) patients with the lung involvement over 3 lesions in the infection group, which was significantly higher than that in the control group (31.70%,97/306)(χ 2=6.965, P=0.008).(4) In the infected group, there were 42.50% (85/200) patients with cavities in the focus, which were significantly higher than that in the control group (26.80%, 82/306)(χ 2=13.487, P=0.000).Conclusion Among the new bacteriological positive PTB patients who combined with other pulmonary infections in the tuberculosis specialist outpatient clinic, the proportion of the elderly patients is higher. The pulmonary lesions are more extensive and often accompanied with cavity formation. |
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| Keywords: | Tuberculosis pulmonary Superinfection Outpatients Comparative study |
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