| 尿路感染分离菌1126株耐药性监测 |
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| 引用本文： | 钮博,刘群,李梅,李峰,陈黎忠,王敏. 尿路感染分离菌1126株耐药性监测[J]. 蚌埠医学院学报, 2010, 35(8): 820-822. DOI: 10.3969/j.issn.1000-2200.2010.08.027 |
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| 作者姓名： | 钮博 刘群 李梅 李峰 陈黎忠 王敏 |
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| 作者单位： | 1. 蚌埠医学院第二附属医院检验科, 安徽蚌埠 233040;2. 蚌埠医学院第一附属医院检验科, 安徽蚌垃 233004 |
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| 基金项目： | 蚌埠医学院自然科学研究资助项目 |
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| 摘 要： | 目的:监测尿路感染患者尿液中分离的病原菌组成及耐药状况。方法:对1126株尿培养分离菌进行鉴定和耐药性分析,特殊耐药株细菌的检测均采用K-B法,并按照CLSI2006年版标准判断敏感率、中介率及耐药率。结果:1126株尿路感染分离菌中大肠埃希菌512株(45.5%),凝固酶阴性葡萄球菌属208株(18.5%),肠球菌属112株(9.9%),白色念珠菌61株(5.4%),变形杆菌55株(4.9%),肺炎克雷伯菌52株(4.6%)以及阴沟肠杆菌、铜绿假单胞菌(棒状杆菌4株、鲍曼不动杆菌等)。其中产超广谱β-内酰胺酶细菌检出率大肠埃希菌为48.0%,肺炎克雷伯菌38.6%,铜绿假单胞菌9.5%,耐甲氧西林凝固酶阴性葡萄球菌78.5%,耐万古霉素肠球菌1.8%,高耐庆大霉素的肠球菌80.4%;仅在大肠埃希菌检出1.4%头孢菌素酶株。碳青霉烯类仍是对G-杆菌(除嗜麦芽窄食单胞菌与黄杆菌)抗菌作用最强的一类抗生素,头孢哌酮/舒巴坦、哌拉西林/他巴唑坦、头孢吡肟等对G-菌亦有很好的抗菌活性;G+菌耐药率普遍较高,仅对万古霉素保持较好的敏感。结论:大肠埃希菌和凝固酶阴性葡萄球菌是尿路感染的主要病原菌。各种病原菌耐药率呈上升趋势,碳青霉烯类和万古霉素分别对G-杆菌和G+球菌抗菌最好、最强的一类抗生素,值得临床关注。
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| 关 键 词： | 尿路感染 细菌 耐药性 微生物敏感性试验 |
| 收稿时间： | 2009-06-22 |
Observation of bacteria drug resistance in urinary tract infection |
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| NIU Bo,LIU Qun,LI Mei,LI Feng,CHEN Li-zhong,WANG Min. Observation of bacteria drug resistance in urinary tract infection[J]. Journal of Bengbu Medical College, 2010, 35(8): 820-822. DOI: 10.3969/j.issn.1000-2200.2010.08.027 |
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| Authors: | NIU Bo LIU Qun LI Mei LI Feng CHEN Li-zhong WANG Min |
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| Affiliation: | 1. Department of Clinical Laboratories, The Second Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233040;2. Department of Clinical Laboratories, The First Affiliated Hospital of Bengbu Medical College, Bengbu Anhui 233004, China |
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| Abstract: | Objective:To monitor the composition and drug resistance of the pathogenic bacteria isolated from the urine of patients with urinary tract infections.Methods:One thousand one hundred and twenty-six drug-resistant bacteria isolated from urine were identified and analyzed,and the special drug-resistant strains were detected by K-B method.The sensitivity rate,intermediate rate and drug resistance rate were determined in accordance with CLSI 2006 standard.Results:Of the 1 126 strains isolated from patients with... |
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| Keywords: | urinary tract infections bacteria drug resistance microbial sensitivity tests |
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