| 光学相干断层扫描血管成像技术（OCTA）观察孔源性视网膜脱离复位术后黄斑区血流 |
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| 引用本文： | 吕湘云,艾明,江双红,陈婷. 光学相干断层扫描血管成像技术（OCTA）观察孔源性视网膜脱离复位术后黄斑区血流[J]. 眼科新进展, 2018, 0(12): 1168-1171. DOI: 10.13389/j.cnki.rao.2018.0276 |
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| 作者姓名： | 吕湘云 艾明 江双红 陈婷 |
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| 作者单位： | 430060 湖北省武汉市，武汉大学人民医院眼科中心 |
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| 摘 要： | 目的 通过光学相干断层扫描血管成像技术（optical coherence tomography angiography，OCTA）观察孔源性视网膜脱离患者视网膜复位术后黄斑区血流情况。方法 对单眼行孔源性视网膜脱离复位术患者进行术后随访。将患眼纳入试验组，将对侧健眼纳入对照组。在患者视网膜复位稳定6个月时使用OCTA对双眼黄斑区进行3 mm×3 mm大小成像，分别计算试验组与对照组浅层视网膜毛细血管（superficial capillary plexus，SCP）层黄斑中心凹无血流管区（foveal avascular zone，FAZ）面积、SCP层和深层视网膜毛细血管（deep capillary plexus，DCP）旁中心凹血流密度及中央视网膜厚度（central retinal thickness，CRT）。对比观察两组眼部血流参数信息，分别评估两组SCP层FAZ面积与CRT的相关性。结果 本研究纳入21例单眼孔源性视网膜脱离复位术后患者。试验组SCP层旁中心凹血流密度为39.50%±7.10%，相比对照组的44.11%±5.72%更小（P=0.026）。试验组CRT为（211.95±30.37）μm，相比对照组的（252.38±15.63）μm更薄（P<0.001）。试验组SCP层FAZ面积、DCP层旁中心凹血流密度分别为（0.34±0.10）mm2、47.67%±9.13%，与对照组的（0.30±0.01）mm2、49.70%±6.10%相比，差异均无统计学意义（均为P>0.05）。两组SCP层FAZ面积与CRT均存在显著负相关（试验组:r=-0.450，P=0.041；对照组:r=-0.527，P=0.014）。结论 孔源性视网膜脱离复位术后患眼黄斑区血流发生显著改变，OCTA观察视网膜脱离复位术后患眼血流有利于监测视网膜结构和功能变化。
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| 关 键 词： | 孔源性视网膜脱离 光学相干断层扫描血流成像技术 黄斑中心凹无血管区 浅层视网膜毛细血管 深层视网膜毛细血管 中央视网膜厚度 |
Observation of the macular vessles after successful rhegmatogenous retinal detachment repair with optical coherence tomography angiography |
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| LV Xiang-Yun,AI Ming,JIANG Shuang-Hong,CHEN Ting. Observation of the macular vessles after successful rhegmatogenous retinal detachment repair with optical coherence tomography angiography[J]. Recent Advances in Ophthalmology, 2018, 0(12): 1168-1171. DOI: 10.13389/j.cnki.rao.2018.0276 |
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| Authors: | LV Xiang-Yun AI Ming JIANG Shuang-Hong CHEN Ting |
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| Affiliation: | Department of Ophthalmology，Renmin Hospital of Wuhan University，Wuhan 430060，Hubei Province，China |
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| Abstract: | Objective To investigate the characteristics of macular vessles after successful rhegmatogenous retinal detachment （RRD） repair with optical coherence tomography angiography （OCTA）.Methods The patients who underwent RRD reattachment surgery with single eye were followed up.The affected eyes were included in the experimental group，and the contralateral healthy eyes were included in the control group.We covered a 3 mm×3 mm area centered on the macular area with OCTA after 6 months of retina stably reattachment，and calculated the superficial foveal avascular zone （FAZ） area，the vessle density of the superficial retinal capillary plexuses（SCP） and the deep retinal capillary plexuses（DCP），and the central retinal thickness （CRT） in both experimental and control groups.We made a comparative observation of ocular blood flow parameters between the two groups.Evaluate the correlation between the superficail FAZ area and the CRT in the two groups separately.Results Total 21 patients who underwent RRD reattachment surgery with single eye were included in the study.The vessle density of the SCP were （39.50%±7.10%） in the experimental group，smaller than the control group［44.11%±5.72% （P=0.026）］.The CRT in the experimental group were（211.95±30.37）μm，thinner than the control group（252.38±15.63）μm（P<0.001）.The superficail FAZ area and the vessel density of the DCP were（0.34±0.10）mm2 and 47.67%±9.13% respectively，no significant difference were detected when compared to the data in the control group［（0.30±0.01）mm2 and 49.70%±6.10% respectively］（P>0.05）.There was a significant negative correlation between the superficial FAZ area and the CRT in both groups separately（the experimental group r=-0.450，P=0.041；the control group r=-0.527，P=0.014）.Conclusion Macular vessles is obviously affected after retina reattachment surgery.Observing the blood flow of the affected eyes with OCTA is helpful to detect the changes of retinal structure and function after retina reattachment. |
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| Keywords: | rhegmatogenous retinal detachment optical coherence tomography angiography foveal avascular zone superficial capillary plexuses deep capillary plexuses central retinal thickness |
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