| 增强光谱钼靶与MRI在乳腺癌诊断中的对比研究 |
| |
| 引用本文： | 徐海东. 增强光谱钼靶与MRI在乳腺癌诊断中的对比研究[J]. 中华全科医学, 2017, 15(4): 650-653. DOI: 10.16766/j.cnki.issn.1674-4152.2017.04.033 |
| |
| 作者姓名： | 徐海东 |
| |
| 作者单位： | 宁波市医疗中心李惠利东部医院放射科, 浙江 宁波 315000 |
| |
| 摘 要： | 目的 比较增强光谱钼靶(CESM)和磁共振成像(MRI)在乳腺癌诊断中的价值。 方法 纳入2016年1-9月经病理证实的40例女性乳腺癌患者作为研究对象。年龄32~76岁,平均(48.6±11.7)岁。未怀孕,未接受乳房切除术、乳房重建术,未接受放化疗,未显示对碘对比剂或其他对比剂过敏。40例患者的病灶共53个,包括:浸润性导管癌22例,共32个病灶;混合癌7例,共7个病灶;浸润性小叶癌5例,共5个病灶;浸润性腺癌3例,共3个病灶;导管内癌1例,共2个病灶;乳腺间叶组织性肉瘤1例,共2个病灶;乳头状癌1例,共2个病灶。全部患者均行增强光谱钼靶和磁共振检查,比较两种方法诊断的敏感度、特异度、准确度、阳性预测值、阴性预测值差异。 结果 40例患者共53个病灶,CESM测量的病灶大小为(32.7±27.7)mm,MRI测量的病灶大小为(33.4±29.5)mm,2组测量结果的差异无统计学意义(P>0.05)。CESM检测方法的敏感度、特异度、准确度、阳性预测值、阴性预测值分别为100.0%、66.7%、90.6%、88.4%、100.0%;MRI为97.4%、53.3%、84.9%、84.1%、88.9%,2种检测方法的诊断性能差异无统计学意义(P>0.05)。 结论 CESM的敏感性、特异性、准确性、阳性预测值、阴性预测值与MRI相当,在乳腺癌诊断中具有一定的应用价值。
|
| 关 键 词： | 增强光谱钼靶 MRI 乳腺癌 |
| 收稿时间： | 2016-11-29 |
A comparative study of contrast-enhanced spectral mammography and magnetic resonance imaging in breast cancer diagnosis |
| |
| Affiliation: | Department of Radiology, Lihuili Eastern Hospital, Ningbo, Zhejiang 315000, China |
| |
| Abstract: | Objective To compare the utility of contrast-enhanced spectral mammography (CESM) and magnetic resonance imaging (MRI) in the diagnosis of breast cancer. Methods From January,2016 to September,2016,a total of 40 women with breast cancer confirmed by pathology were enrolled as research object to performed with CESM and BMRI.Age ranged was from 32 to 76 years,with an average age was (48.6±11.7) years.No pregnant,without receiving the mastectomy,or breast reconstruction,without chemotherapy,or shown to iodine contrast agent or other contrast agent allergy.There were 53 piece of lesions in 40 patients,including 32 piece of lesions in 22 cases of infiltrating ductal carcinoma;7 piece of lesions in 7 cases of mixed tumor;5 piece of lesions in 5 cases of invasive lobular carcinoma;3 piece of lesions in 3 cases of invasive adenocarcinoma;2 piece of lesions in 1 cases of intraductal carcinoma;2 piece of lesions in 1 cases of leaf tissue tumor of the breast meat;2 piece of lesions in 1 cases of papillary carcinoma.The average maximum dimensions of the lesions were measured.The differences in sensitivity,specification,accuracy,positive predictive value and negative predictive value were compared between the two methods. Results Fifty-there lesions were identified.The mean size of lesions tested by CESM and MRI were (32.7±27.7) mm and (33.4±29.5) mm,which show no differences between the two methods (P>0.05).CESM sensitivity was 100%(vs.97.4% for MRI),specificity was 66.7%(vs.53.3% for MRI),accuracy was 90.6%(vs.84.9% for MRI),positive predictive value was 88.4%(vs.84.1% for MRI),and negative predictive value was 100%(vs.88.9% for MRI) for breast cancer diagnosis.There was no statistically significant difference between the two methods for the diagnostic indexes (P>0.05). Conclusion Compared with MRI,CESM can provide great sensitivity,specification,accuracy,PPV and NPV,which has potential application value in breast cancer detection. |
| |
| Keywords: | |
|
| 点击此处可从《中华全科医学》浏览原始摘要信息 |
|
点击此处可从《中华全科医学》下载免费的PDF全文 |
|
