| 某三甲医院EB病毒感染的临床回顾性分析 |
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| 引用本文： | 许大兵, 孙余婕, 沈佐君. 某三甲医院EB病毒感染的临床回顾性分析[J]. 中华疾病控制杂志, 2018, 22(2): 191-194. doi: 10.16462/j.cnki.zhjbkz.2018.02.021 |
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| 作者姓名： | 许大兵 孙余婕 沈佐君 |
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| 作者单位： | 安徽医科大学附属省立医院安徽省临床检验中心, 安徽 合肥 230001 |
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| 摘 要： | 目的 探讨某三甲医院一年来EB病毒（epstein-barr virus，EBV）感染的情况，分析常见病种的构成及临床特征，为EBV感染及相关疾病的防治提供科学的理论依据。方法 回顾分析该院2015年10月~2016年9月采用荧光PCR法检测EBV核酸载量，并对检测结果及患者的临床资料进行分析。结果 1 313例血浆标本中EBV脱氧核糖核酸（deoxyribonucleic acid，DNA）阳性标本314例，总体阳性检出率为23.91%，其中女性患者的阳性检出率为21.60%，男性为25.27%，男女不同性别的阳性检出率无差异（（口恶）2=2.26，P=0.133）。在不同年龄段的EBV-DNA阳性检出率出现两个高峰，分别为1~10岁和61~70岁。不同季节间的EBV阳性检出率也有不同，其中秋季最高为36.44%，冬季最低为13.00%。该院科室之间患者EBV的阳性检出率前五位的依次为：儿科（40.91%）、放疗科（39.30%）、血液科（18.50%）、感染科（16.98%）、重症加强护理病房（intensive care unit，ICU）（15.79%）。不同疾病的EBV阳性检出率不同。结论 EBV的阳性检出率与国内其他地区报道相似，有年龄、季节差异，无性别差异。EBV感染的临床表现复杂多样。
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| 关 键 词： | 疱疹病毒4型 人 感染 DNA |
| 收稿时间： | 2016-10-28 |
| 修稿时间： | 2017-05-25 |
A retrospective analysis on the prevalence and clinical characteristics of epstein-barr virus infection in one tertiary first-class hospital |
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| XU Da-bing, SUN Yu-jie, SHEN Zuo-jun. A retrospective analysis on the prevalence and clinical characteristics of epstein-barr virus infection in one tertiary first-class hospital[J]. CHINESE JOURNAL OF DISEASE CONTROL & PREVENTION, 2018, 22(2): 191-194. doi: 10.16462/j.cnki.zhjbkz.2018.02.021 |
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| Authors: | XU Da-bing SUN Yu-jie SHEN Zuo-jun |
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| Affiliation: | Affiliated Provincial Hospital of Anhui Medical University, Anhui Provincial Center for Clinical Laboratories, Hefei 230001, China |
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| Abstract: | Objective To investigate the prevalence and clinical characteristics of epstein-barr (EB) virus infection in the hospital and to provide scientific theoretical basis for the prevention and treatment of EBV infection and related diseases. Methods A retrospective study was conducted among EB infected patients in our hospital from October 2015 to September 2016. The relationship between detection results and clinical data of patients were analyzed. Results The plasma samples from 1 313 patients were collected and detected for EB infection. 314 cases were found EBV-DNA positive with a total positive rate of 23.91%. The positive rates of female patients (21.60%) and male patients (25.27%) showed no significant difference ((口恶)2=2.26, P=0.133). The positive rate of EBV-DNA varied in different age groups, peaking at 1-10 and 61-70 years old. The positive rate altered by different seasons was highest (36.44%) in autumn and lowest in winter (13.00%). There was significant difference in the EB infection rate among different departments of the hospital. The top five departments with high infection rate of EB were pediatrics (40.91%), radiotherapy (39.30%), hematology (18.50%), infectious disease (16.98%) and intensive care unit (15.79%). The positive rate of EBV-DNA in different diseases was different. Conclusions Infection rate of EB virus in our hospital is comparable with that in other regions of China. The infection rate varies in different seasons, ages and departments in the hospital. The clinical manifestations of EB virus infection are complex and varied. |
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| Keywords: | Herpesvirus 4 human Infection DNA |
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