| 206例液氮冷冻治疗皮赘的临床分析 |
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| 引用本文： | 陈伟,黄江英,张文霞,谭燕娜,朱江. 206例液氮冷冻治疗皮赘的临床分析[J]. 中华全科医学, 2018, 16(1): 67. DOI: 10.16766/j.cnki.issn.1674-4152.000019 |
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| 作者姓名： | 陈伟 黄江英 张文霞 谭燕娜 朱江 |
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| 作者单位： | 1. 杭州市萧山区第三人民医院皮肤科, 浙江 杭州 311251; |
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| 基金项目： | 2015年浙江省医药卫生一般研究计划项目(2015-KYA131) |
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| 摘 要： | 目的 研究和评价液氮冷冻对发生于各部位皮赘的治疗效果及不良反应的影响。 方法 以杭州市萧山区第三人民医院2015年5月-2017年5月收治的206名皮赘患者为样本案例,以性别和不同年龄段进行分组,以35~50岁为低龄组,共55人,以51~72岁为高龄组,共151人。以棉签涂抹液氮的方式进行冷冻治疗。通过治疗后皮赘脱落情况判定治疗效果。治疗后观察病损处及询问患者,对液氮冷冻治疗后产生的一些不良反应做出评价。 结果 以年龄与性别分组测得数据经统计分析Z值为0.217与0.789,差异无统计学意义(P>0.05),表明年龄和性别不是影响治疗效果的关键性因素。根据治疗数据结果表明,液氮冷冻治疗皮赘具有很好的疗效,其中一次性治愈达到114例,占到55.3%,总有效例数(含治愈、显著及有效3个疗效级别)达到202例,占比98.1%。不良反应发生结果表明,在冷冻治疗后存在水肿、水泡、血泡、瘢痕、感染等不良反应,其中水肿和水泡发生率较高,分别占到69.9%和63.1%。 结论 液氮冷冻治疗皮赘,治愈率高,效果显著,但该方法也存在一定的不良反应发生风险,如产生水肿、水泡、病损处感染等情况,在治疗后续处理中需注意观察并及时做好对应的医护处理。但总体来说不良反应影响较低,且该治疗方案操作简单,成本低廉,是一项值得推广和深入研究的治疗方法。
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| 关 键 词： | 液氮冷冻 皮赘 皮肤软纤维瘤 |
| 收稿时间： | 2017-08-23 |
Dermatology experience with liquid nitrogen cryotherapy for dermatofibroma: 206 cases |
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| Affiliation: | Department of Dermatology, the Third People's Hospital of Xiaoshan, Hangzhou, Zhejiang 311251, China |
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| Abstract: | Objective To study and evaluate the effect of liquid nitrogen freezing on the treatment of skin lesions in various sites and the adverse reactions. Methods A total of 206 patients with skin tumor treated in our hospital from May, 2015 to May, 2017 were included in the study. The patients were divided into groups according to gender and age. A total of 55 people in 35-50 years of age group. A total of 151 people in 51-72 years old group. Cryotherapy was performed by applying liquid nitrogen with cotton swabs. The therapeutic effect was evaluated by the treatment of the skin loss after treatment. After the treatment, the lesion was observed and the patients were asked to evaluate the adverse effects of liquid nitrogen cryotherapy. Results The data measured by age and sex groups were statistically analyzed. The P value was 0.217 and 0.789, and there was no significant difference (P>0.05). Age and sex are not the key factors that influence the treatment outcome. According to the treatment results, cryotherapy skin tag has good curative effect.The one-time cure rate reached 114 cases, accounting for 55.3%. The total effective rate (including cure, significant and effective therapeutic class three) reached 202 cases, accounting for 98.1%. Adverse reaction results show that the existence of adverse reactions of edema, blisters, bleeding blister, scar and infection after cryosurgery, the higher incidence of edema and blisters, respectively accounting for 69.9% and 63.1%. Conclusion Cryotherapy of skin neoplasm with high cure rate and significant effect, but this method also has certain adverse risks such as edema, blisters and lesions, etc. Observation is needed for the subsequent processing and timely medical treatments. But overall effect and adverse reaction is low. The treatment has the advantages of simple operation as well as low cost, which is worthy of promotion and further research. |
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