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A quantitative systems pharmacology model of blood coagulation network describes in vivo biomarker changes in non‐bleeding subjects |
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| Authors: | D. Lee S. Nayak S. W. Martin A. C. Heatherington P. Vicini F. Hua |
| Affiliation: | 1. PharmaTherapeutics Clinical Research, Pfizer Inc., Cambridge, MA, USA;2. Pharmacometrics, Global Innovative Pharma Business, Pfizer Inc., Cambridge, MA, USA;3. Pharmacokinetics, Dynamics and Metabolism – New Biological Entities, Pfizer Inc., San Diego, CA, USA |
| Abstract: | |
| Keywords: | blood coagulation factor VIIa hemophilia prothrombin fragment 1 + 2 systems biology |