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Development of extended‐release solid dispersion granules of tacrolimus: evaluation of release mechanism and human oral bioavailability
Authors:Daisuke Tsunashima  Kazunari Yamashita  Ken‐ichi Ogawara  Kazuhiro Sako  Tadashi Hakomori  Kazutaka Higaki
Affiliation:1. Pharmaceutical Research and Technology Labs., Astellas Pharma Inc., Yaizu, Shizuoka, Japan;2. Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, Okayama University, Kita‐ku, Okayama, Japan;3. Astellas Ireland Co., Ltd., Damastown Road, Damstown Industrial Park, Mulhuddart, Dublin 15, Ireland
Abstract:
Keywords:controlled and sustained release systems  pharmaceutics and drug delivery
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