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Fear of hypoglycemia and its determinants in insulin‐treated patients with type 2 diabetes mellitus
Authors:Naoki Sakane  Kazuhiko Kotani  Kokoro Tsuzaki  Masami Nishi  Kaoru Takahashi  Takashi Murata  Kazunori Yamada  Kentaro Okazaki  Katsuyuki Yanagisawa  Kenichi Yamada  Nobuichi Kuribayashi  Yasuo Totsuka  Toru Hiyoshi  Motoji Naka  Masatake Sugimoto  Yuji Aoki  Masako Waki  Miyuki Furuya  Haruko Kitaoka  Mariko Oishi  Ikki Shimizu  Hiroaki Miyaoka  Akira Okada  Toshikazu Yamamoto
Affiliation:1. Division of Preventive Medicine, Clinical Research Institute, Kyoto, Japan;2. Department of Clinical Laboratory Medicine, Juichi Medical University, Tochigi, Japan;3. Okada Clinic, Fukuoka, Japan;4. Hyogo Health Service Association, Hyogo, Japan;5. Diabetes Center, National Hospital Organization Kyoto Medical Center, Kyoto, Japan;6. Department of Development for Community‐oriented Healthcare System, Nagoya University Graduate School of Medicine, Nagoya, Japan;7. Souen Diabetes Clinic, Sapporo, Japan;8. Kenichi Yamada Internal Medicine Clinic, Miyagi, Japan;9. Misakinaika Clinic, Chiba, Japan;10. Chofu Tozan Hospital, Chofu, Japan;11. Japanese Red Cross Medical Center, Tokyo, Japan;12. Department of Internal Medicine, Asama General Hospital, Nagano, Japan;13. Tokyo Adventist Hospital, Tokyo, Japan;14. Department of Internal Medicine, National Hospital Organization Matsumoto Medical Center, Nagano, Japan;15. Shizuoka City Shizuoka Hospital, Shizuoka, Japan;16. Department of Endocrinology, Tenri Hospital, Nara, Japan;17. Department of Internal Medicine, Seikeikai Hospital, Osaka, Japan;18. Oishi Clinic, Kyoto, Japan;19. Department of Diabetes, The Sakakibara Heart Institute of Okayama, Okayama, Japan;20. Saiseikai Matsuyama Hospital, Ehime, Japan;21. Kariyushikai Heartlife Hospital, Okinawa, Japan
Abstract:The aim of the present study was to investigate the prevalence of fear of hypoglycemia, in association with severe hypoglycemia and social factors, in insulin‐treated patients with type 2 diabetes mellitus. A questionnaire survey on hypoglycemia and patient–physician communication was carried out in 355 patients with insulin‐treated type 2 diabetes mellitus patients at 16 hospitals and clinics. A fear of hypoglycemia was reported by 27.7% of patients. A stepwise logistic regression analysis found that severe hypoglycemia during the past 1 year was a significant determinant of fear of hypoglycemia (odds ratio 2.16, 95% confidence interval 1.06–4.41; P = 0.034), and age (odds ratio 1.02, 95% confidence interval 1.00–1.05, P = 0.038) and living alone (odds ratio 1.93, 95% confidence interval 1.00–3.73, P < 0.05) were significantly higher in patients with fear of hypoglycemia than in those without it.
Keywords:Fear  Hypoglycemia  Insulin  Type   2 diabetes
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