Effect of theo-polyphenols on hepatic histology of hyperlipidemia model in quails |
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| Authors: | Yongsheng Ke Xiangming Zhu Zhendong Zhao |
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| Affiliation: | (1) Yijishan Hospital, Wannan Medical College, 241001 Wuhu, Anhui |
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| Abstract: | To observe the protective effect of theo polyphenols (TP) on hepatic histology of hyperlipidemia model in quails. Methods: Model of hyperlipidemia in quails was established. The 75 male quails were divided randomly into 5 groups, 15 in each group. The non hyperlipidemia group (normal control group) was fed with ordinary forage. The hyperlipidemia group (hyperlipidemia control group) was fed with high lipid forage. The three TP groups were fed with high lipid forage together with a low (25 mg/kg), middle (50 mg/kg) and high (100 mg/kg) dose of TP respectively. The total experimental period was 6 weeks for all the quails. Results: TP could prevent the increase of serum total cholesterol (TC), triglycerides (TG), low density lipoprotein cholesterol (LDL C) and liver index (LI) caused by high lipid food, thus showing protective dose dependant effect on hepatic histology in hyperlipidemia. Conclusion: TP has the effect of regulating serum lipids in preventing and treating fatty liver. |
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| Keywords: | theo polyphenols hyperlipidemia fatty liver histology quail |
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