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A Computer Program for Aligning a cDNA Sequence with a Genomic DNA Sequence |
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| Authors: | Liliana Florea George Hartzell Zheng Zhang Gerald M. Rubin Webb Miller |
| Abstract: | We address the problem of efficiently aligning a transcribed and spliced DNA sequence with a genomic sequence containing that gene, allowing for introns in the genomic sequence and a relatively small number of sequencing errors. A freely available computer program, described herein, solves the problem for a 100-kb genomic sequence in a few seconds on a workstation. |
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