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中老年人血压水平与脑卒中患病率及患病风险的相关性研究
引用本文:陈昕,赵海娜,李晓波,宋慧. 中老年人血压水平与脑卒中患病率及患病风险的相关性研究[J]. 现代预防医学, 2022, 0(16): 2899-2902. DOI: 10.20043/j.cnki.MPM.202202036
作者姓名:陈昕  赵海娜  李晓波  宋慧
作者单位:江苏省苏北人民医院,江苏 扬州 225001
摘    要:目的 研究中老年人群中血压水平与脑卒中患病率及患病风险之间的关系。方法 采用分层整群抽样方法,对扬州市广陵区40岁及以上常住居民开展问卷调查、体格检查和实验室检查。通过对年龄分层,采用单因素和多因素logistic回归分析不同年龄组血压与脑卒中患病率及患病风险的关系。结果 3 999例有效样本中,男性1 904例(47.61%),女性2 095例(52.39%);其中脑卒中243例(6.08%),高血压1 900例(47.51%),糖尿病929例(23.23%),血脂异常943例(23.58%),高血压患者中脑卒中211例(86.83%)。男性(χ2 = 9.539,P = 0.002)、高龄(t = - 13.683,P<0.001)、缺乏运动(χ2 = 15.568,P<0.001)、吸烟史(χ2 = 40.799,P<0.001)、高血压(t = - 9.149,P<0.001)、高血糖(t = - 6.832,P<0.001)、低高密度脂蛋白胆固醇(t = 3.509,P<0.001)、肥胖(t = - 4.964,P<0.001)均是脑卒中重要危险因素。随着年龄和血压的增加,脑卒中的患病率增加。对年龄进行分层,并对危险因素进行校正,60岁以下人群中脑卒中患病风险随血压升高而显著增加;收缩压≥160 mm Hg脑卒中患病风险是收缩压<130 mm Hg的8.13倍;舒张压≥110 mm Hg脑卒中患病风险是舒张压<80 mm Hg的28.54倍。60岁及以上人群中收缩压≥150 mm Hg脑卒中患病风险开始增加;收缩压≥160 mm Hg脑卒中患病风险是收缩压<130 mm Hg的2.12倍;舒张压与脑卒中患病风险之间无显著相关性。结论 高血压是脑卒中的重要危险因素,根据不同的年龄,设定相应的降压目标是有效预防脑卒中的重要途径。

关 键 词:血压  年龄  脑卒中患病率

Correlation between blood pressure levels and the prevalence and risk of stroke in middle-aged and elderly people
CHEN Xin,ZHAO Hai-na,LI Xiao-bo,SONG Hui. Correlation between blood pressure levels and the prevalence and risk of stroke in middle-aged and elderly people[J]. Modern Preventive Medicine, 2022, 0(16): 2899-2902. DOI: 10.20043/j.cnki.MPM.202202036
Authors:CHEN Xin  ZHAO Hai-na  LI Xiao-bo  SONG Hui
Affiliation:Northern Jiangsu People’s Hospital, Yangzhou, Jiangsu 225001, China
Abstract:Objective To explore the relationship between blood pressure and the prevalence and risk of stroke in middle-aged and aged people. Methods People aged over 40 years old were enrolled by stratified cluster sampling method in Guangling, Yangzhou. The relevant information was collected by inquiry survey, physical measurement, and laboratory test. We analyzed the relationship between blood pressure and stroke prevalence in different age groups by age stratification analysis and single or multiple logistic regression. Results Among the 3 999 valid samples, 1 904 were males (47.61%) and 2 095 were females (52.39%). There were 243 cases of stroke (6.08%), 1 900 cases of hypertension (47.51%), 929 cases of diabetes (23.23%), 943 cases of dyslipidemia (23.58%), and 211 cases of stroke (86.83%) in hypertensive patients. Men (χ2=9.539, P=0.002), advanced age (t=-13.683, P<0.001), smokers (χ2=40.799, P<0.001), hypertension (t=-9.149, P<0.001), hyperglycemia (t=-6.832, P<0.001), low HDL-C (t=3.509, P<0.001), obesity (t=-4.964, P<0.001) and people who lacked exercise (χ2=15.568, P<0.001) were risk factors for stroke. The prevalence of stroke increased with aging and blood pressure. Age stratification revealed that the risk of stroke increased significantly with the increase of blood pressure in people under 60 years old. When systolic blood pressure (SBP) ≥160 mm Hg, the risk was 8.13 times higher than SBP<130 mm Hg. When diastolic blood pressure (DBP) ≥110 mm Hg, the risk was 28.54 times higher than DBP<80 mm Hg. For people aged 60 and above, the risk of stroke with SBP≥150 mm Hg began to increase. When SBP≥160 mm Hg, the risk was 2.12 times higher than SBP <130 mm Hg. However, there was no significant relationship between DBP and stroke. Conclusion Hypertension is an important risk factor for stroke. According to different ages, setting age-specific antihypertensive goals is crucial for the effective prevention of stroke.
Keywords:Blood hypertension  Age  Prevalence of stroke
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