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2018—2021年成都市自愿咨询检测人群HIV确证阳性特征分析
引用本文:金宇,崔莹,刘晓玲,黄怡丹. 2018—2021年成都市自愿咨询检测人群HIV确证阳性特征分析[J]. 现代预防医学, 2022, 0(12): 2281-2286
作者姓名:金宇  崔莹  刘晓玲  黄怡丹
作者单位:成都医学院第二附属医院·核工业四一六医院检验科,四川 成都 610051
摘    要:目的 了解成都市艾滋病自愿咨询检测(VCT)人群人类免疫缺陷病毒(HIV)确证阳性人群特征,为艾滋病防控提供依据。方法 收集2018年4月—2021年6月于成都市某VCT门诊咨询并完成抗-HIV筛查人群门诊数据,统计HIV确证情况,分析确证者人群特征;采用Cochran - Armitage trend法评价不同高危类型求询者HIV确证阳性率趋势;追踪不确定者随访结果。结果 共完成3 590份抗 - HIV样本筛查,确证阳性率为20.45%,且各年度HIV确证结果比较差异无统计学意义(χ2 = 7.812,P = 0.252)。男性(χ2 = 78.938,P<0.001)、年龄<30岁(χ2 = 12.894,P = 0.005)、男男性行为(χ2 = 50.850,P<0.001)、注射吸毒史(χ2 = 21.477,P<0.001)、配偶/固定性伴阳性(χ2 = 16.171,P<0.001)、商业异性性行为史(χ2 = 41.147,P<0.001)、非商业非固定异性性行为史(χ2 = 6.030,P = 0.014)、医疗相关问题人群(χ2 = 7.644,P = 0.006)HIV确证阳性率较同类别人群更高。确证阳性者“新国八条”整体知晓率40.33%,低于非确证阳性者的51.16%(χ2 = 27.400,P<0.001)。男男性行为(Z = - 21.593,P<0.001)、医疗相关问题阳性率(Z = - 7.246,P = 0.007)呈下降趋势;商业异性性行为(Z = 4.712,P = 0.030)、非商业非固定异性性行为阳性率(Z = 10.330,P = 0.001)呈上升趋势。126例不确定者共54例(42.86%)在建议时间内随访复查,其中转为确证阳性43例(79.63%)。结论 VCT人群整体HIV确证阳性率较高,应将男性、年龄<30岁、男男性行为、注射吸毒史、配偶/固定性伴阳性、商业异性性行为史、非商业非固定异性性行为史、医疗相关问题人群列为宣传重点人群,加强艾滋病防控知识宣教,同时应注意目标人群行为变化特征,加强不确定者随访管理。

关 键 词:HIV  自愿咨询检测  抗 - HIV筛查  确证试验

Analysis of HIV positive confirmation characteristics of voluntary counseling and testing population in Chengdu from 2018 to 2021
JIN Yu,CUI Ying,LIU Xiao-ling,HUANG Yi-dan. Analysis of HIV positive confirmation characteristics of voluntary counseling and testing population in Chengdu from 2018 to 2021[J]. Modern Preventive Medicine, 2022, 0(12): 2281-2286
Authors:JIN Yu  CUI Ying  LIU Xiao-ling  HUANG Yi-dan
Affiliation:Department of Laboratory Medicine, The Second Affiliated Hospital of Chengdu Medical College, Nuclear Industry 416 Hospital, Chengdu, Sichuan 610051, China
Abstract:Objective To understand the characteristics of human immunodeficiency virus (HIV) confirmed positive population in Chengdu voluntary counselling and testing (VCT) population to provide a basis for HIV prevention and control. Methods The outpatient data of patients who consulted and completed anti-HIV screening in a VCT outpatient clinic in Chengdu were collected between April 2018 and June 2021. The HIV confirmation status was statistically analyzed and the characteristics of confirmed population were analyzed. Cochran-Armitage trend method was used to evaluate the confirmed positive rate of HIV among different high-risk types of inquirers. The follow-up status of unconfirmed people was tracked. Results A total of 3 590 anti-HIV samples were screened, and the confirmation rate was 20.45%. Males (χ2=78.938, P<0.001), age <30 years (χ2=12.894, P=0.005), men who have sex with men (χ2=50.850, P<0.001), history of injection drug use (χ2=21.477, P<0.001), positive spouse/regular partner (χ2=16.171, P<0.001), history of commercial heterosexual sex (χ2=41.147, P<0.001), history of non-commercial non-regular heterosexual sex (χ2=6.030, P=0.014), and medical-related problems (χ2=7.644, P=0.006) had higher rates of confirmed HIV positivity than their counterparts. The overall awareness rate of “New 8 rules” was 40.33% among confirmed positive patients, which was lower than that of 51.16% among non-confirmed positive patients (χ2=27.400, P<0.001). There was a decreasing trend for men who have sex with men (Z=-21.593, P<0.001) and medical-related problems (Z=-7.246, P=0.007), and an increasing trend for commercial heterosexual sex (Z=4.712, P=0.030) and non-commercial non-fixed heterosexual sex (Z=10.330, P=0.001). Out of the 126 cases of uncertainty, 54 cases (42.86%) were followed up and retested within the recommended time, of which 43 cases (79.63%) were confirmed positive. Conclusion The VCT population as a whole has a high rate of confirmed HIV positivity, and should include men, age <30 years, men who have sex with men, history of injecting drug use, positive spouse/regular sexual partner, history of commercial heterosexual sex, history of non-commercial non-regular heterosexual sex, and people with medical-related problems as key populations for the promotion of HIV prevention and control. We should pay attention to the behavioral change characteristics of the target population and strengthen the follow-up of the indeterminate management.
Keywords:HIV  Voluntary counseling and testing  Anti-HIV screening  Confirmatory test
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