| 抑郁在老年人日常生活活动能力和认知功能状况的中介效应研究 |
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| 引用本文： | 袁玫1,3,4,杜金1,3,王婉晨1,3,4,范成鑫2,3,4,刘馨璐1,3,4,宋佳2,3,4,王相印1. 抑郁在老年人日常生活活动能力和认知功能状况的中介效应研究[J]. 现代预防医学, 2022, 0(24): 4500-4504. DOI: 10.20043/j.cnki.MPM.202206101 |
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| 作者姓名： | 袁玫1 3 4 杜金1 3 王婉晨1 3 4 范成鑫2 3 4 刘馨璐1 3 4 宋佳2 3 4 王相印1 |
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| 作者单位： | 1.潍坊医学院公共卫生学院,山东 潍坊 261053;2.潍坊医学院管理学院,山东 潍坊 261053;3.“健康山东”重大社会风险预测与治理协同创新中心,山东 潍坊 261053;4.健康相关重大社会风险预警协同创新中心,上海 200032 |
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| 摘 要： | 目的 探讨抑郁在老年人日常生活活动能力和认知功能状况间的中介作用。方法 选取2018年CHARLS调查中5 397例≥60岁的老年人样本,采用日常生活活动能力量表（ADL）、流调中心抑郁水平评定量表（CES - 10）及简易精神状态量表（MMSE）进行测量;使用单因素分析、Pearson相关分析、逐步回归分析及Bootstrap中介检验进行数据分析。结果 老年人认知障碍率为30.64%。ADL和认知功能间呈正相关（r = 0.255,P＜0.01）,ADL与认知功能均对抑郁呈负相关关系（r = - 0.295、 - 0.252,P＜0.01）。回归结果显示ADL得分和抑郁得分均对认知功能状况有影响（t = 12.107、 - 8.079,P＜0.001）。ADL对认知功能的总效应值为0.126,直接效应值为0.106,抑郁对认知功能的中介效应值为0.020。结论 老年人认知功能状况不容乐观,ADL、抑郁均是老年人认知功能的影响因素,抑郁在老年人ADL与认知功能间起部分中介作用。
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| 关 键 词： | 老年人 认知功能 抑郁 日常生活活动能力 中介作用 |
The mediating effect of depression on the ability of daily living and cognitive function in the elderly |
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| YUAN Mei,DU Jin,WANG Wan-chen,FAN Cheng-xin,LIU Xin-lu,SONG Jia,WANG Xiang-yin,AI Xu-feng,LI Qiu-sha,ZHAO Zi-xuan,YIN Wen-qiang. The mediating effect of depression on the ability of daily living and cognitive function in the elderly[J]. Modern Preventive Medicine, 2022, 0(24): 4500-4504. DOI: 10.20043/j.cnki.MPM.202206101 |
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| Authors: | YUAN Mei DU Jin WANG Wan-chen FAN Cheng-xin LIU Xin-lu SONG Jia WANG Xiang-yin AI Xu-feng LI Qiu-sha ZHAO Zi-xuan YIN Wen-qiang |
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| Affiliation: | *School of Weifang Medical University, Weifang, Shandong 261053, China |
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| Abstract: | Objective To investigate the mediating effect of depression on the ability of daily living and cognitive function in the elderly. Methods A total of 5 397 elderly patients aged ≥60 years were selected from the 2018 CHARLS survey, and the Activity of Daily (ADL) Scale, CES-10 depression Level Rating Scale (CES-10) and MMSE were used for measurement. Data were analyzed by univariate analysis, Pearson correlation analysis, stepwise regression analysis, and Bootstrap mediation test. Results The rate of cognitive impairment was 30.64%. ADL was positively correlated with cognitive function (r=0.255, P<0.01), ADL and cognitive function were negatively correlated with depression (r=-0.295 and -0.252, P<0.01). Regression results showed that both ADL score and depression score had an impact on cognitive function (t=12.107 and -8.079, P<0.001). The total effect value of ADL on cognitive function was 0.126, the direct effect value was 0.106, and the mediating effect value of depression on cognitive function was 0.020. Conclusion The cognitive function of the elderly is not optimistic. Both ADL and depression are influential factors of the cognitive function of the elderly, and depression plays a partial mediating role in the relationship between ADL and cognitive function. |
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| Keywords: | Elderly Cognitive function Depression Daily living ability Intermediary role |
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