| OSAHS患者应用改良悬雍垂腭咽成形术治疗的效果观察 |
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| 引用本文： | 许镇斌,杨小雄,庄燕云,席艳君,陈鹏,巫琪,袁美蓉,纪楚莲. OSAHS患者应用改良悬雍垂腭咽成形术治疗的效果观察[J]. 国际医药卫生导报, 2022, 28(12): 1656-1660. DOI: 10.3760/cma.j.issn.1007-1245.2022.12.007 |
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| 作者姓名： | 许镇斌 杨小雄 庄燕云 席艳君 陈鹏 巫琪 袁美蓉 纪楚莲 |
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| 作者单位： | 东莞市长安医院耳鼻咽喉科,东莞 523843 |
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| 基金项目： | 东莞市社会科技（一般）项目（201950715022644） |
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| 摘 要： | 目的 探讨阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者应用改良悬雍垂腭咽成形术治疗的效果。方法 回顾性分析2015年1月至2020年1月东莞市长安医院耳鼻咽喉科收治的108例OSAHS患者临床资料,将患者以随机数字表法分为试验组和对照组,各54例。对照组男26例、女28例,年龄（39.34±3.26）岁,采取单纯腭咽成形术;试验组男28例、女26例,年龄（38.84±3.54）岁,采取改良悬雍垂腭咽成形术。比较两组患者术前及术后1个月、3个月、6个月呼吸暂停低通气指数（AHI）、Epworth嗜睡量表（ESS）、最低血氧饱和度（LSaO2）、用力呼出75%肺活量时的瞬间呼气流量（MEF75）、第1秒用力呼吸容积（FEV1）、呼气峰流速（PEF）指标,评价两组患者临床疗效。计量资料采用独立样本t检验,计数资料采用χ2检验。结果 术后1个月、3个月、6个月,试验组AHI值分别为（18.36±1.89）次/h、（15.24±1.35）次/h、（14.09±1.25）次/h,均低于对照组（20.95±1.74）次/h、（18.63±1.42）次/h、（16.34±1.08）次/h,ESS评分分别为（7.24±1.56）分、（6.95±0.69）分、（5.67±0.35）分,均低于对照组（9.29±1.47）分、（8.33±0.72）分、（8.01±0.54）分,差异均有统计学意义（均P<0.05）。术后3个月、术后6个月,试验组MEF75指标为（89.85±7.69）%、（96.34±8.44）%,均高于对照组（84.29±7.30）%、（89.36±7.95）%,FEV1指标为（95.30±7.41）%、（99.20±7.25）%,均高于对照组（92.34±6.71）%、（94.24±6.03）%,PEF指标为（91.29±4.36）%、（95.37±5.88）%,均高于对照组（87.63±5.01）%、（91.24±5.24）%,LSaO2指标为（85.01±6.34）%、（89.01±7.42）%,均高于对照组（80.63±5.96）%、（84.39±6.33）%,差异均有统计学意义（均P<0.05）。试验组总有效率为96.30%（52/54）,显著优于对照组85.19%（46/54）,差异有统计学意义（χ2=3.967,P=0.046）。结论 改良悬雍垂腭咽成形术治疗OSAHS患者近期及远期疗效更佳,对改善OSAHS患者的生活质量有重大意义。
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| 关 键 词： | 改良悬雍垂腭咽成形术 OSAHS 疗效 |
| 收稿时间： | 2022-03-16 |
Observation on the effect of H-uvulopalatopharyngoplasty for OSAHS patients |
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| Xu Zhenbin,Yang Xiaoxiong,Zhuang Yanyun,Xi Yanjun,Chen Peng,Wu Qi,Yuan Meirong,Ji Chulian. Observation on the effect of H-uvulopalatopharyngoplasty for OSAHS patients[J]. International Medicine & Health Guidance News, 2022, 28(12): 1656-1660. DOI: 10.3760/cma.j.issn.1007-1245.2022.12.007 |
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| Authors: | Xu Zhenbin Yang Xiaoxiong Zhuang Yanyun Xi Yanjun Chen Peng Wu Qi Yuan Meirong Ji Chulian |
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| Affiliation: | Department of Otolaryngology, Dongguan Chang'an Hospital, Dongguan523843, China |
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| Abstract: | Objective To investigate the efficacy of H-uvulopalatopharyngoplasty in patientswith obstructive sleep apnea hypopnea syndrome (OSAHS). Methods The clinical data of 108 patients with OSAHS admitted to Department ofOtolaryngology, Dongguan Chang'an Hospital from January 2015 to January 2020were retrospectively analyzed. All patients were divided into an experimentalgroup and a control group according to the random number table, with 54 casesin each group. In the control group, there were 26 males and 28 females, aged(39.34±3.26) years; in the experimental group, there were 28 males and 26females, aged (38.84±3.54) years. The control group underwent simplepalatopharyngoplasty, and the experimental group underwentH-uvulopalatopharyngoplasty. Apnea hypopnea index (AHI), Epworth SleepinessScale (ESS), lowest blood oxygen saturation (LSaO2), momentaryexpiratory flow at 75% (MEF75), forced expiratory volume in 1 second (FEV1),and peak expiratory flow rate (PEF) were compared between the two groups beforesurgery and 1, 3, and 6 months after surgery, and the clinical efficacies ofthe two groups were evaluated. Independent sample t test was used for the measurement data, and χ2 test was used for the count data. Results The AHI value of the experimental group were (18.36±1.89) times/h 1month after surgery, (15.24±1.35) times/h 3 months after surgery, and(14.09±1.25) times/h 6 months after surgery, respectively, which were lowerthan those of the control group [(20.95±1.74) times/h, (18.63±1.42) times/h,and (16.34±1.08) times/h], the ESS scores were (7.24±1.56) points, (6.95±0.69)points, and (5.67±0.35) points, respectively, which were lower than those ofthe control group [(9.29±1.47) points, (8.33±0.72) points, and (8.01±0.54)points], with statistically significant differences (all P<0.05). The MEF75 index of the experimental group was(89.85±7.69)% 3 months after surgery and (96.34±8.44)% 6 months after surgery,which were higher than those of the control group [(84.29±7.30)% and(89.36±7.95)%], the FEV1 indexes were (95.30±7.41)% and (99.20±7.25)%, whichwere higher than those of the control group [(92.34±6.71)% and (94.24±6.03)%],the PEF indexes were (91.29±4.36)% and (95.37±5.88) %, which were higher thanthose of the control group [(87.63±5.01)% and (91.24±5.24)%], and the LSaO2 indexes were (85.01±6.34)% and (89.01±7.42)%, which were higher than those ofthe control group [(80.63±5.96)% and (84.39±6.33)%], with statisticallysignificant differences (all P<0.05).The total effective rate of the experimental group was 96.30% (52/54), whichwas significantly higher than 85.19% (46/54) of the control group, with astatistically significant difference (χ2=3.967, P=0.046). Conclusion H-uvulopalatopharyngoplasty has better short-term and long-termefficacies in the treatment of OSAHS patients, which is of great significancefor improving the quality of life in patients with OSAHS. |
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| Keywords: | H-uvulopalatopharyngoplasty OSAHS Curative effect |
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