三种手术方式治疗cT1N0期甲状腺癌的近期疗效及安全性比较 Comparison of the short-term efficacy and the safety of three kinds of surgical procedures for patients with cT1N0 thyroid cancer期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

三种手术方式治疗cT1N0期甲状腺癌的近期疗效及安全性比较

引用本文：	李涛,焦良和,朱正才,董文武,姚天琦. 三种手术方式治疗cT1N0期甲状腺癌的近期疗效及安全性比较[J]. 中华普外科手术学杂志(电子版), 2020, 14(6): 624-627. DOI: 10.3877/cma.j.issn.1674-3946.2020.06.025

作者姓名：	李涛焦良和朱正才董文武姚天琦

作者单位：	^1. 225300 泰州市人民医院普外科^2. 110001 中国医科大学第一附属医院甲状腺外科

摘要：	目的对比三种手术方式治疗cT1N0期甲状腺癌的近期疗效及安全性。方法回顾性队列研究2017年1月至2019年5月73例cT1N0期甲状腺癌患者资料，根据术式不同分为3组。25例患者纳入开放组，将实施全乳晕入路腔镜手术治疗的24例患者纳入全乳晕组，将经口腔前庭入路腔镜手术治疗的24例患者纳入经口腔组。采用SPSS23.0软件进行处理，围术期相关指标、视觉模拟评估量表(VAS)、Vancouver疤痕评定量表(VSS)评分以( ±s)表示，多组间采用单因素方差分析；疗效、并发症用χ²检验，P<0.05为差异有统计学意义。结果经口腔组、全乳晕组治疗总有效率(91.7%、87.5%)均比开放组(64.0%)高(P<0.05)；经口腔组、全乳晕组手术时间长于开放组(P<0.05)，但术中出血量、术后引流量及术后住院时间均比开放组低(P<0.05)；经口腔组术后3 d、1个月的VAS评分、VSS评分<全乳晕组<开放组(P<0.05)；经口腔组、全乳晕组并发症发生率(8.3%、8.3%)比开放组低(32.0%)，差异有统计学意义(P<0.05)。结论相比开放手术，腔镜下甲状腺手术治疗cT1N0期甲状腺癌的疗效更佳、并发症更少、住院时间更短，可作为优选治疗方案。
关键词：	甲状腺肿瘤腹腔镜手术后并发症外科手术疗效比较研究
收稿时间：	2020-06-09
Comparison of the short-term efficacy and the safety of three kinds of surgical procedures for patients with cT1N0 thyroid cancer

Tao Li,Lianghe Jiao,Zhengcai Zhu,Wenwu Dong,Tianqi Yao. Comparison of the short-term efficacy and the safety of three kinds of surgical procedures for patients with cT1N0 thyroid cancer[J]. Chinese Journal of Operative Procedures of General Surgery(Electronic Version, 2020, 14(6): 624-627. DOI: 10.3877/cma.j.issn.1674-3946.2020.06.025

Authors:	Tao Li Lianghe Jiao Zhengcai Zhu Wenwu Dong Tianqi Yao

Affiliation:	^1. Department of General Surgery, People's Hospital of Taizhou city, Jiangsu 225300, China^2. Department of Thyroid Surgery, the First Affiliated Hospital of China Medical University, Liaoning 110001, China

Abstract:	ObjectiveTo compare the short-term efficacy and the safety of three kinds of surgical procedures for patients with cT1N0 stage thyroid cancer. MethodsA retrospective cohort study was conducted in 73 patients with cT1N0 thyroid cancer from January 2017 to May 2019, who were divided into three groups according to different surgical methods, including 25 patients in the open group, 24 patients in the whole areola group and 24 patients in the transoral group. Statistical analysis were performed by using SPSS 23.0 software. Measurement data, such as perioperative related indicators, visual analogue scale (VAS) and Vancouver Scar Scale (VSS) scores were expressed as ( ±s), and were examined by using One-way analysis of variance. Short-term efficacy and postoperative complications were analyzed by using χ² test A P value <0.05 was considered as statistically significant difference. ResultsThe total effective rate of 91.7% amd 87.5% in the trans-oral group and total areola group was higher than 64.0% in the open group (P<0.05); while the operation time in the trans-oral group and total areola group was longer than that in the open group (P<0.05) However, in terms of the intraoperative blood loss, postoperative drainage, and postoperative hospital stay were much lower than those in the open group respectively (P<0.05); the VAS score and VSS score at POD3 and 1 month in the oral group were less than those in the total areola group and the open group (P<0.05); The incidence of postoperative complications of 8.33% and 8.33% was much lower in the transoral group and the whole areola group than 32.0% in the open group (P<0.05). ConclusionCompared with open surgery, endoscopic thyroid surgery has better curative effect, fewer complications, and shorter hospital stay in the surgical treatment of cT1N0 stage thyroid cancer, and could be used as the preferred therapuetic treatment.

Keywords:	Thyroid neoplasms Laparoscopes Postoperative complications Surgical procedures operative Comparative effectiveness research

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