A Proposal of a Clinically Based Classification for Idiopathic Granulomatous Mastitis |
| |
| Authors: | Rami Yaghan1Shadi Hamouri1Nehad M Ayoub2Lamees Yaghan1Tagleb Mazahreh1 |
| |
| Affiliation: | 1Department of General Surgery and Urology, Faculty of Medicine, Jordan University of Science and Technology, Jordan.2Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Jordan. |
| |
| Abstract: | Objectives: There is no consensus regarding the surgical or immunosuppressive treatment of idiopathicgranulomatous mastitis (IGM). This study aimed to introduce a clinical classification system for IGM that might facilitateits treatment and predict recurrence. Methods: We analyzed the management of 68 patients with IGM at (Princess BasmaTeaching Hospital and King Abdulla University Hospital (1994-2016) to find out if distinct patterns of presentationexist according to the following parameters: presence of a painful or painless breast mass, local inflammation, abscessformation, communication to the skin, and extra-mammary manifestation. Results: We identified four distinct patterns ofIGM: A: (13.23 %) A hard, painless breast mass. B: (52.94 %) A hard, painful breast mass with gross inflammation.C: (26.47 %) A breast abscess-like presentation. D: (7. 35 %) A subacute presentation with ulceration, sinus, or fistulaformation. Erythema nodosum might complicate any of these patterns. Wide local excision in pattern A was curativewith zero recurrence rate. The recurrence rates in patterns B and C were 22.20 % and 50.00 %. Patterns B, C, andD were treated by a combination of surgery and prednisolone. In keeping with this, recent literature is in favor ofa wider use of immunosuppression especially in the presence of pus and extra-mammary findings. Conclusion: IGMcould be classified into 4 distinct patterns according to the presenting signs and symptoms. These patterns correlatedwith treatment, recurrence rate, and the gross operative findings. This is the first step toward a classification for IGM.Multicenter and Meta-analysis studies are essential for a comprehensive prognostic classification. Treatment of IGMin any institution should be the responsibility of a multidisciplinary team. |
| |
| Keywords: | idiopathic granulomatous mastitis immunosuppressive therapy wide local excision Recurrence classification system |
|
| 点击此处可从《Asian Pacific journal of cancer prevention》浏览原始摘要信息 |
|
点击此处可从《Asian Pacific journal of cancer prevention》下载免费的PDF全文 |
|
