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蛇床子现代药理学作用及临床应用的研究进展
引用本文:宋宜蕾,侯雪芹,郝吉福. 蛇床子现代药理学作用及临床应用的研究进展[J]. 神经药理学报, 2019, 9(6): 58-63. DOI: 10.3969/j.issn.2095-1396.2019.06.011
作者姓名:宋宜蕾  侯雪芹  郝吉福
作者单位:山东第一医科大学,山东省医学科学院,泰安, 271016, 中国
基金项目:国家自然科学基金项目(No.81703901),山东省重点研究项目(No.2019GSF108069),山东省中医药管理局项目(No.2019-0361)
摘    要:蛇床子是伞形科植物蛇床的干燥成熟果实,是一种传统的中药材,在古代史书中均有对其的记载,临床上主要以外用为主,多用于治疗妇科,外科,皮肤科等疾病。蛇床子含有多种化学成分,主要含有香豆素类,挥发油类,糖类以及多种微量元素。蛇床子素是蛇床子发挥药效的主要成分之一,现代药理学研究发现,蛇床子素在心脑血管系统,中枢神经系统,内分泌系统,免疫系统等方面的疾病均有具有的治疗效果。

关 键 词:蛇床子  化学成分  蛇床子素  药理作用  机制

Advances in Research on Modern Pharmacological Effects and Clinical Application of Cnidium
SONG Yi-lei,HOU Xue-qin,HAO Ji-fu. Advances in Research on Modern Pharmacological Effects and Clinical Application of Cnidium[J]. Journal of Hebei North University(Medical Edition), 2019, 9(6): 58-63. DOI: 10.3969/j.issn.2095-1396.2019.06.011
Authors:SONG Yi-lei  HOU Xue-qin  HAO Ji-fu
Affiliation:Shandong First Medical University & Shandong Academy of Medical Sciences,Taian,271016,China
Abstract:Cnidium is a dry and mature fruit of the genus Umbelliferae. It is a traditional Chinese medicinal material. It has been recorded in ancient history books. It is mainly used in clinical practice and is mainly used for the treatment on gynecology and surgery. For diseases such as dermatology,male diseases are mainly based on internal medicine. Cnidium contains a variety of chemical components,mainly containing coumarins,volatile oils,sugars and various trace elements. Osthole is one of the main components of the effect of Cnidium. Modern pharmacological studies have found that osthole has therapeutic effects on diseases such as cardiovascular and cerebrovascular system,central nervous system,endocrine system and immune system.
Keywords:cnidium  chemical composition  osthole  pharmacological action  mechanism  
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