Large sequence polymorphisms classify Mycobacterium tuberculosis strains with ancestral spoligotyping patterns |
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| Authors: | Flores Laura Van Tran Narayanan Sujatha DeRiemer Kathryn Kato-Maeda Midori Gagneux Sebastien |
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| Affiliation: | Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California San Francisco, USA. |
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| Abstract: | Genomic deletion analysis revealed that strains of Mycobacterium tuberculosis exhibiting spoligotyping patterns with almost all spacers present belong either to a strain lineage that includes the W-Beijing strain family or to the ancestral strain lineage of M. tuberculosis. |
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