| 心肌缺血预适应对单支动脉闭塞性急性心肌梗死患者的影响 |
| |
| 引用本文： | 张航向,龚卫琴,陶凌. 心肌缺血预适应对单支动脉闭塞性急性心肌梗死患者的影响[J]. 心脏杂志, 2000, 12(4): 273-275. DOI: 10.13191/j.chj.2000.04.23.zhanghx.011 |
| |
| 作者姓名： | 张航向 龚卫琴 陶凌 |
| |
| 作者单位： | 第四军医大学西京医院老年病科,陕西,西安,710032 |
| |
| 摘 要： | 目的 :观察心肌缺血预适应 （IPC）对急性心肌梗死 （AMI）患者并发症及预后的影响。方法 :对照分析 40例无 IPC的 AMI患者 （A组 ）和 5 0例有 IPC的 AMI患者 （B组 ）的近期临床资料。结果 :B组梗死后泵功能障碍发生率及程度、磷酸肌酸激酶 （CPK）峰值、并发症均显著低于 A组 ,近期预后有改善。结论 :缺血预适应组 CPK的峰值降低 ,梗死后所致心肌坏死面积减小 ,从而使泵功能障碍的发生率降低、梗死后室性心律失常、 度以上房室传导阻滞及再灌注性心律失常发生率减少。这可能是 IPC使 AMI患者死亡率降低的主要原因。
|
| 关 键 词： | 心肌梗死 急性 心肌缺血预适应 心肌再灌注 心肌保护 |
Effect of ischemic preconditioning on the patients with acute myocardial infarction |
| |
| ZHANG Hang-xiang,GONG Wei-qin,TAO Ling. Effect of ischemic preconditioning on the patients with acute myocardial infarction[J]. Chinese Heart Journal, 2000, 12(4): 273-275. DOI: 10.13191/j.chj.2000.04.23.zhanghx.011 |
| |
| Authors: | ZHANG Hang-xiang GONG Wei-qin TAO Ling |
| |
| Abstract: | AIM: The effect of ischemic preconditioning(IPC) on complication and prognosis of the patients with myocardial infarction (AMI) was investigated. METHODS: The materials of 40 AMI patients without IPC (group A) and 50 AMI patients with IPC (group B) were analysed. RESULTS: Rate and degree of ventricular function failure, peak of CPK and complication in group B were significantly lower than those in group A (P<0.01), the recently prognosis in group B was improved. CONCLUSIONS: Decrease of CPK peak or extent of infarction results in lower rates of pump function failure, decrease of ventricular arrythmia and reperfusion arrythmia in the patients with IPC, it may be the main reason that IPC can reduce mortality of the patients with AMI |
| |
| Keywords: | myocardial infarction acute ischemic preconditioning myocardial reperfusion cardioprotection |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《心脏杂志》浏览原始摘要信息 |
|
点击此处可从《心脏杂志》下载免费的PDF全文 |
