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难治性便秘综合治疗及影响因素的评价
引用本文:许琳,宋志强,王智凤,柯美云. 难治性便秘综合治疗及影响因素的评价[J]. 基础医学与临床, 2008, 28(4): 387-390
作者姓名:许琳  宋志强  王智凤  柯美云
作者单位:1. 青岛市立医院消化内科,山东青岛,266011
2. 中国医学科学院中国协和医科大学北京协和医院消化内科,北京,100730
摘    要:目的评价综合治疗对难治性便秘的疗效及影响因素。方法将84例难治性便秘分为非重叠组和重叠组。应用个体化综合治疗4周,观察便秘症状评分变化及总有效率,分析IC患者的重叠症状和心理障碍状态对疗效的影响。结果(1)84例便秘患者中,重叠组和非重叠组分别占40.5%和59.5%。(2)重叠组和非重叠组的总有效率分别为50.0%和78.0%(P<0.05)。(3)对37例IC患者的心理测试调查显示,59.4%(22/37)有心理障碍状态,重叠组和非重叠组伴有心理障碍状态对治疗的总有效率分别为4.8%和31.5%(P<0.05)。结论适合个体化的综合治疗使多数难治性便秘缓解症状,但伴有重叠症状,尤其心理障碍状态则影响疗效。

关 键 词:难治性便秘  心理障碍状态  重叠症  综合治疗
文章编号:1001-6325(2008)04-0387-04
收稿时间:2007-04-10
修稿时间:2007-04-11

Evaluation of clinical efficacy of integrative therapy and influencing factors in patients with intractable constipation
XU Lin,SONG Zhi-qiang,WANG Zhi-feng,KE Mei-yun. Evaluation of clinical efficacy of integrative therapy and influencing factors in patients with intractable constipation[J]. Basic Medical Sciences and Clinics, 2008, 28(4): 387-390
Authors:XU Lin  SONG Zhi-qiang  WANG Zhi-feng  KE Mei-yun
Abstract:Objective To evaluate the effect of integrative therapy and influencing factors in patients with intractable constipation (IC). Methods Eighty-four consecutive IC patients were divided into non overlap and overlap groups. All patients received individualized integrative therapeutic regimen for 4 weeks. The symptom scores of constipation and total effective rates were evaluated. Influencing factor of therapeutic effect in IC was analyzed.Results (1) IC of overlap group and non overlap group accounted for 40.5% (34/84) and 59.5% (50/84), respectively. (2)The total effective rates were 50.0% and 78.0% in overlap and non-overlap group, respectively(P<0.05). (3) Thirty-seven patients received psychological assessment and 59.4% (22/37) of them had psychological dysfunctions. The total effective rates were 4.8% and 31.5% in overlap and non overlap group with psychological dysfunctions respectively (P<0.05). Conclusion The integrative individualized therapy was effective in terms of relieving symptoms in patients with IC. However, overlap symptoms, and psychological dysfunction may have negative impact.
Keywords:intractable constipation  overlap symptoms  psychological dysfunction  integrative therapy
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