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淮安地区食管癌患者ABO血型的相关性研究
引用本文:陈 星1,刘帅帅2,3,' target='_blank'>4,李前文3. 淮安地区食管癌患者ABO血型的相关性研究[J]. 现代肿瘤医学, 2015, 0(18): 2604-2605. DOI: 10.3969/j.issn.1672-4992.2015.18.15
作者姓名:陈 星1  刘帅帅2  3  ' target='_blank'>4  李前文3
作者单位:1.界首市人民医院,安徽 界首 236500;2.蚌埠医学院,安徽 蚌埠 233000;3.解放军第82医院肿瘤科,江苏 淮安 223001;4.枣庄市立医院,山东 枣庄 277100
基金项目:国家高科技研究发展计划(863计划)(编号:2014AA020901);南京军区医学科技创新课题(编号:08MA036)
摘    要:目的:调查淮安市食管癌患者ABO血型分布特点,分析其相关性并探讨各种血型物质在食管癌发生中的作用。方法:收集我院初治的食管癌患者263例为病例组,随机抽取淮安市中心血站同时期1000例健康献血人群ABO血型资料为对照组。统计分析两组ABO血型分布频率,进行相关性分析和血型的相对危险率分析。结果:病例组A型血占27.4%,对照组为17.8%,A型血频率在病例组与对照组之间存在显著性差异。病例组B型血、O型血和AB型血型分别占31.6%、30.0%、11.0%,对照组分别占35.7%、36.2%、10.3%,均无显著性差异。相对危险率A型血者为1.54,B型血者为0.89,O型血者为0.83,AB型血者为1.06。结论:淮安ABO血型分布与食管癌的发生具有一定的关系,提示血型物质A抗原可能是食管癌的一个危险因子。

关 键 词:ABO血型  食管癌  危险因子

The relationship between ABO blood type and esophageal cancer in Huaian China
Chen Xing1,Liu Shuaishuai2,3,' target='_blank'>4,Li Qianwen3. The relationship between ABO blood type and esophageal cancer in Huaian China[J]. Journal of Modern Oncology, 2015, 0(18): 2604-2605. DOI: 10.3969/j.issn.1672-4992.2015.18.15
Authors:Chen Xing1  Liu Shuaishuai2  3  ' target='_blank'>4  Li Qianwen3
Affiliation:1.The Jieshou People's Hospital of Anhui Province,Anhui Jieshou 236500,China;2.Medical College of Bengbu,Anhui Bengbu 233000,China;3.Department of Oncology,82th Hospital of PLA,Jiangsu Huaian 223001,China;4Zaozhuang Hospital of Shandong,Shandong Zaozhuang 277100,China.
Abstract:Objective:To investigate ABO blood group distribution characteristics of patients with esophageal cancer in Huaian China.Methods:To select 263 patients with esophageal cancer in Huaian as the case group,1000 cases of healthy blood donors in Huaian blood center during the same period as control group.Results:In case group,type A blood occupied 27.4%,17.8%in the placebo group(P<0.05).For B,O and AB blood group,there were 31.6%,30.0%,11.0% in case group, and in control group there were 35.7%,36.2%,10.3%(P>0.05).Relative risk type A was 1.54,type B was 0.89, type O was 0.83,AB was 1.06.Conclusion:The ABO blood group distribution and esophageal cancer has some correlation.Blood group antigen A is an important risk factor for esophageal cancer.
Keywords:ABO blood group  esophageal cancer  risk factors
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