| CAR-T 细胞在肿瘤治疗中的研究进展 |
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| 引用本文： | 赵玲娣(综述),高全立(审校). CAR-T 细胞在肿瘤治疗中的研究进展[J]. 中国肿瘤临床, 2015, 42(3): 190-194. DOI: 10.3969/j.issn.1000-8179.20141675 |
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| 作者姓名： | 赵玲娣(综述) 高全立(审校) |
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| 作者单位： | 作者单位:郑州大学附属肿瘤医院,河南省肿瘤医院(郑州市450008) |
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| 摘 要： | 以嵌合型抗原受体（chimeric antigen receptor，CAR ）为基础的细胞免疫治疗是一种新的治疗恶性肿瘤的模式，为部分晚期实体瘤患者带来治愈的希望。选择合适的目标靶分子、应用安全的基因转导方法、防治CAR-T细胞治疗的不良反应、将使CAR-T细胞造福越来越多的晚期肿瘤患者。
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| 关 键 词： | 嵌合型抗原受体 免疫治疗 肿瘤 |
| 收稿时间： | 2014-10-07 |
Research progress of CAR T-cell in tumor therapy |
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| Lingdi ZHAO,Quanli GAO. Research progress of CAR T-cell in tumor therapy[J]. Chinese Journal of Clinical Oncology, 2015, 42(3): 190-194. DOI: 10.3969/j.issn.1000-8179.20141675 |
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| Authors: | Lingdi ZHAO Quanli GAO |
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| Affiliation: | The Affiliated Hospital of Zhengzhou University and Henan Cancer Hospital, Zhengzhou 450008, China |
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| Abstract: | Adoptive cell transfusion based on chimeric antigen receptor (CAR) is a new approach for treating malignant diseases and even advanced malignancies. More patients with advanced malignancies are expected to benefit from CAR T-cells once the suitable target molecules are selected, the safe method of gene transduction is applied, and the side effects of CAR T-cells are prevented. |
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| Keywords: | chimeric antigen receptor immunotherapy tumor |
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