| 口服固体缓控释制剂研究进展 |
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| 引用本文： | 李腊蕊, 朱家壁. 口服固体缓控释制剂研究进展[J]. 中国药科大学学报, 2006, 37(1): 14-17. |
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| 作者姓名： | 李腊蕊 朱家壁 |
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| 作者单位： | 1.中国药科大学药物制剂研究所 |
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| 基金项目： | 教育部新世纪优秀人才支持计划;广东省博士启动基金;国家自然科学基金 |
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| 摘 要： | 近年来,口服缓控释技术发展迅速,种类繁多,其中典型的给药系统包括骨架片、渗透泵制剂、多单元给药系统等。这几类制剂是口服固体缓控释制剂的研究热点和主流,也是与实际生产应用结合最为紧密的制剂类型。本文综述了这几类口服缓控释制剂的最新研究动态。
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| 关 键 词： | 口服缓控释 骨架片 渗透泵 多单元给药系统 |
| 文章编号： | 1000-5048(2006)01-0014-04 |
| 收稿时间： | 2006-11-15 |
| 修稿时间： | 2005-11-15 |
Drug discovery based on pharmacological interference with glycometabolism |
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| SUN Hong-bin. Drug discovery based on pharmacological interference with glycometabolism[J]. Journal of China Pharmaceutical University, 2006, 37(1): 14-17 |
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| Authors: | SUN Hong-bin |
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| Affiliation: | Institude of Pharmaceutics, China Pharmceutical University, Nanjing 210009, China |
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| Abstract: | There are a large number of controlledrelease technologies available for dosage form development.Typical oral solid controlled-release drug delivery systems(DDSs) embrace:matrix tablets;osmotic systems,such as the asymmetric membrane technology or swellable core technology;and multiple-unit drug delivery system as well.These DDSs are the hot spot and main trend of oral solid DDSs,and they are tightly integrated with the large-scale production.This review provides the latest advances on these research areas. |
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| Keywords: | oral controlled-release matrix tablets osmotic systems multiple-unit drug delivery system |
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