| 脾转移性神经内分泌癌1例及文献复习 |
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| 引用本文： | 贾静,石新兰,张宁,李玉广,崔铁莉,李振强. 脾转移性神经内分泌癌1例及文献复习[J]. 蚌埠医学院学报, 2011, 36(2): 150-152,155 |
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| 作者姓名： | 贾静 石新兰 张宁 李玉广 崔铁莉 李振强 |
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| 作者单位： | 北京市石景山医院病理科, 100043 |
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| 摘 要： | 目的:探讨脾转移性神经内分泌癌的临床及病理形态学特点、诊断及鉴别诊断。方法:应用石蜡切片光镜观察、免疫组织化学染色等方法,结合临床表现、影像学资料对1例脾转移性神经内分泌癌进行分析,并复习文献。结果:患者男性,30岁,临床症状主要表现为疲乏、发热、左上腹痛、中度脾肿大伴脾破裂,彩色多普勒超声和CT检查发现脾内占位。病理检查见癌组织位于脾脏自发性破裂口的周围实质(局限于红髓)及脾门软组织内,癌细胞排列成实性、梁状、腺样、假菊形团样结构,间质纤维组织分隔瘤细胞团;细胞中等大小,形态相对一致,胞质嗜酸性,核居中,圆形或卵圆形,核仁清楚,病理性核分裂象少见,脾门淋巴结及血管可见癌累犯。免疫组织化学示癌细胞CD56(2+~3+),Syn (1+),CgA、CK (±)。结论:脾转移性神经内分泌癌临床甚罕见,形态与发生于其他器官的神经内分泌癌类似,免疫组织化学有助诊断。
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| 关 键 词： | 脾肿瘤 肿瘤转移 癌 神经内分泌 病理学 临床 |
| 收稿时间： | 2010-08-09 |
Metastatic neuroendocrine carcinoma of the spleen: a case report and review of the literature |
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| JIA Jing,SHI Xin-lan,ZHANG Ning,LI Yu-guang,CUI Tie-li,LI Zhen-qiang. Metastatic neuroendocrine carcinoma of the spleen: a case report and review of the literature[J]. Journal of Bengbu Medical College, 2011, 36(2): 150-152,155 |
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| Authors: | JIA Jing SHI Xin-lan ZHANG Ning LI Yu-guang CUI Tie-li LI Zhen-qiang |
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| Affiliation: | Department of Pathology, Beijing Shijingshan Hospital, Beijing 100043, China |
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| Abstract: | Objective:To investigate the clinicopathological features,diagnosis and differential diagnosis for metastatic neuroendocrine carcinoma of the spleen.Methods:Paraffin imbedding section,morphological observation and immunohistochemistry,with analysis of clinical manifestation and imaging data,were applied in one case of metastatic neuroendocrine carcinoma of the spleen,and the related literatures were reviewed.Results:A 30-year-old male presented lassitude,fever,pain in the left upper quadrant,moderate spleno... |
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| Keywords: | spleen neoplasms neoplasm metastasis carcinoma neuroendocrine pathology clinical |
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