| 腹腔镜胆总管探查术联合腹腔镜胆囊切除术治疗胆囊结石合并胆总管结石患者临床疗效研究 |
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| 引用本文： | 付前广,李倩,冯小雪,王勇,邓如兵,崔畅. 腹腔镜胆总管探查术联合腹腔镜胆囊切除术治疗胆囊结石合并胆总管结石患者临床疗效研究[J]. 实用肝脏病杂志, 2021, 24(4): 589-592. DOI: 10.3969/j.issn.1672-5069.2021.04.034 |
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| 作者姓名： | 付前广 李倩 冯小雪 王勇 邓如兵 崔畅 |
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| 作者单位： | 610100 成都市 四川大学华西医院龙泉医院普通外科(付前广,王勇,邓如兵);消化内科(李倩,冯小雪,崔畅) |
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| 基金项目： | *四川省高等学校重点科研项目(编号:18A320040) |
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| 摘 要： | 目的 探讨采用腹腔镜胆总管探查术(LCBDE)联合腹腔镜胆囊切除术(LC)治疗胆囊结石合并胆总管结石患者的临床疗效.方法 2016年5月 ～2020年7月我院诊治的85例胆囊结石合并胆总管结石患者,其中41例接受LCBDE联合LC术,另44例接受在ERCP下行十二指肠镜Oddi括约肌切开术(EST)联合LC术治疗,术后...
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| 关 键 词： | 胆石症 腹腔镜胆囊切除术 腹腔镜胆总管探查术 治疗 |
| 收稿时间： | 2021-03-19 |
Clinical efficacy of laparoscopic common bile duct exploration and laparoscopic cholecystectomy combination in the treatment of patients with cholecystolithiasis and choledocholithiasis |
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| Fu Qianguang,Li Qian,Feng Xiaoxue,et al. Clinical efficacy of laparoscopic common bile duct exploration and laparoscopic cholecystectomy combination in the treatment of patients with cholecystolithiasis and choledocholithiasis[J]. Journal of Clinical Hepatology, 2021, 24(4): 589-592. DOI: 10.3969/j.issn.1672-5069.2021.04.034 |
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| Authors: | Fu Qianguang Li Qian Feng Xiaoxue et al |
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| Affiliation: | Department of General Surgery, Longquan Hospital, West China Hospital, Sichuan University, Chengdu 610100, Sichuan Province, China |
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| Abstract: | Objective The aim of this study was to explore the clinical efficacy of laparoscopic common bile duct exploration (LCBDE) and laparoscopic cholecystectomy (LC) combination in the treatment of patients with cholecystolithiasis and choledocholithiasis. Methods A total of 85 patients with cholecystolithiasis and choledocholithiasis were enrolled in this study between May 2016 and July 2020, 41 patients received LCBDE and LC combination, and another 44 patients received endoscopic sphincterotony (EST) under endoscopic retrograde cholangiopancreatography (ERCP) and LC. All patients were followed-up for 12 months. The visual analogue scales (VAS) score was applied to evaluate post-operational pain, and peripheral blood lymphocyte subsets was assayed by FCM. Results There were no significant differences respect to the surgical success rates and stone residual rates between the two groups (97.6% vs.93.2% and 2.4% vs. 6.8%, P>0.05), the usage rate of analgesic pumps and VAS score were 36.6% and (2.5±0.5), both significantly lower than 59.1% and (3.1±0.6) in the control (P<0.05), and the stone recurrence rate as confirmed by sonography one year after operation in the observation group was 2.4%,significantly lower than 15.9% in the control (P<0.05); there were no significant differences respect to biochemical parameters between the two groups two weeks after operation (P>0.05); the percentages of peripheral blood CD3+, CD4+ and CD8+ cells as well as the ratio of D4+/CD8+ cells in the observation group were (52.8±7.1)%, (40.3±7.5)%, (21.0±5.2)% and (1.9±0.3), not significantly different as compared to [(54.7±6.9)%, (41.0±7.2)%, (22.5±5.6)% and (1.8±0.3), respectively, P>0.05] in the control; there was no significant difference in the incidence of post-operational complications between the two groups (2.4% vs. 9.1%, P>0.05). Conclusion The surgical success rate of LCBDE and LC combination in the treatment of patients with cholecystolithiasis and choledocholithiasis is high, and is still a good approach for the management of patients with this kind of entity. |
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| Keywords: | Cholecystolithiasis Choledocholithiasis Laparoscopic common bile duct exploration Laparoscopic cholecystectomy Therapy |
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