| 颅内出血患者合并非酒精性脂肪性肝病情况分析 |
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| 引用本文： | 晋颖,周卫真,冯世兵,汪湃. 颅内出血患者合并非酒精性脂肪性肝病情况分析[J]. 实用肝脏病杂志, 2021, 24(3): 367-370. DOI: 10.3969/j.issn.1672-5069.2021.03.016 |
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| 作者姓名： | 晋颖 周卫真 冯世兵 汪湃 |
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| 作者单位： | 100013 北京市和平里医院消化科(晋颖,冯世兵,汪湃); 首都医科大学附属北京朝阳医院消化科(周卫真) |
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| 基金项目： | 北京市和平里医院科研项目(编号:2017-1-03)。 |
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| 摘 要： | 目的 回顾颅内出血(ICH)患者合并非酒精性脂肪性肝病(NAFLD)情况并分析其危险因素.方法 2010年1月～2020年6月我院收治的ICH患者146例,使用超声检查诊断脂肪性肝病,采用单因素和多因素Logistic回归分析,明确合并NAFLD的危险因素.结果 在本组146例ICH患者中,经超声检查发现NAFLD者5...
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| 关 键 词： | 非酒精性脂肪性肝病 颅内出血 格拉斯哥昏迷评分 血脂 |
| 收稿时间： | 2020-09-17 |
Prevalence of nonalcoholic fatty liver diseases in patients with intracerebral hemorrhage |
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| Jin Ying,Zhou Weizhen,Feng Shibing,et al. Prevalence of nonalcoholic fatty liver diseases in patients with intracerebral hemorrhage[J]. Journal of Clinical Hepatology, 2021, 24(3): 367-370. DOI: 10.3969/j.issn.1672-5069.2021.03.016 |
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| Authors: | Jin Ying Zhou Weizhen Feng Shibing et al |
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| Affiliation: | Department of Gastroenterology, Hepingli Hospital, Beijing 100013 |
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| Abstract: | Objective The aim of this study was to investigate the prevalence of nonalcoholic fatty liver diseases(NAFLD)in patients with intracerebral hemorrhage(ICH).Methods A total of 146 patients with ICH were treated in our hospital between January 2010 and June 2020,and all underwent sonography for the diagnosis of NAFLD.The univariate and multivariate Logistic regression analysis was applied to confirm the factors for NAFLD coexistence.Results Out of our series,52 patients(35.6%)were found with underlying NAFLD;the percentage of type two diabetes mellitus(T2DM)in patients with NAFLD was 32.7%,significantly higher than 12.8%(P<0.05)in patients without NAFLD,the body mass index in patients with NAFLD was(25.4±2.4)kg/m 2,significantly higher than[(23.1±2.7)kg/m 2,P<0.05]in patients without NAFLD,the blood high-density lipoprotein(HDL)level in patients with NAFLD was(1.4±0.5)mmol/L,significantly lower than(1.8±0.5)mmol/L in patients without NAFLD,the blood triglyceride level was(4.2±1.6)mmol/L,significantly higher than[(2.2±1.1)mmol/L,P<0.05]in patients without NAFLD,the percentage of large intracerebral bleeding volume in patients with NAFLD was 75.0%,significantly higher than 39.4%(P<0.05)in patients without NAFLD,and the percentage of lowGlasgow coma score(GCS)in patients with NAFLD was 67.3%,significantly higher than 37.2%(P<0.05)in patients without NAFLD,while there were not significant differences as respect to the percentages of high blood pressure,smoking,cardiovascular diseases,vascular malformation,increased fasting plasma glucose,serum alanine aminotransferase and aspartate aminotransferase,and infection between the two groups(P>0.05);multivariate Logistic analysis showed that coincidence of T2DM,large intracerebral bleeding and lower GCS were the independent risk factors for underlying NAFLD in this circumstance,and normal blood HDL level was the protective factor for patients without NAFLD(P<0.05).Conclusions The presence of T2DM,intracerebral hematoma volume greater than 30 ml and GCS score less than 10 in patients with ICH might hints the presence of NAFLD,which remind the clinicians dealing appropriately with them in clinical practice. |
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| Keywords: | Nonalcoholic fatty liver diseases Intracerebral hemorrhage Glasgow coma score Hyperlipoproteinemia |
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