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Robust anti‐obesity and metabolic effects of a dual GLP‐1/glucagon receptor peptide agonist in rodents and non‐human primates |
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| Authors: | A. Konkar PhD D. C. Hornigold PhD J. L. Trevaskis PhD R. Jackson PhD M. Fritsch Fredin PhD R. Jansson‐Löfmark PhD J. Naylor PhD A. Rossi PhD M. A. Bednarek PhD N. Bhagroo H. Salari S. Will S. Oldham G. Hansen MSc M. Feigh PhD T. Klein PhD J. Grimsby PhD S. Maguire L. Jermutus PhD C. M. Rondinone PhD M. P. Coghlan PhD |
| Affiliation: | 1. MedImmune LLC, Gaithersburg, MD, USABoth authors made an equivalent contribution to this paper.;2. MedImmune Ltd, Cambridge, UK;3. MedImmune LLC, Gaithersburg, MD, USA;4. AstraZeneca R&D, M?lndal, Sweden;5. Gubra ApS, H?rsholm, Denmark |
| Abstract: | |
| Keywords: | bodyweight cynomolgus monkeys diet‐induced obese mice dual agonist GLP‐1 receptor knock‐out mice glucagon glucagon‐like peptide‐1 glucose tolerance liraglutide obesity type 2 diabetes |