| 视网膜脱离患者脑白质纤维束的异常变化 |
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| 引用本文： | 徐云芳,梁荣斌,张丽娟,潘逸聪,葛倩敏,李秋玉,石文卿,周琼,邵毅. 视网膜脱离患者脑白质纤维束的异常变化[J]. 眼科新进展, 2021, 0(6): 545-548. DOI: 10.13389/j.cnki.rao.2021.0113 |
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| 作者姓名： | 徐云芳 梁荣斌 张丽娟 潘逸聪 葛倩敏 李秋玉 石文卿 周琼 邵毅 |
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| 作者单位： | 330006 江西省南昌市,南昌大学第一附属医院眼科 |
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| 摘 要： | 目的 利用弥散张量成像数据探讨视网膜脱离(RD)患者脑白质纤维束的异常变化和该疾病潜在的病理生理机制.方法 选取南昌大学第一附属医院眼科收治的RD患者30例(男16例,女14例)作为观察组,另招募30名健康人(男16人,女14人)作为对照组.所有受试者的功能性磁共振成像(MRI)数据均由八通道相控阵头线圈3-Tesla...
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| 关 键 词： | 视网膜脱离 弥散张量成像 基于纤维束示踪的空间统计学技术 |
Abnormal changes in cerebral white matter fiber bundle in patients with retinal detachment |
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| XU Yunfang,LIANG Rongbin,ZHANG Lijuan,PAN Yicong,GE Qianmin,LI Qiuyu,SHI Wenqing,ZHOU Qiong,SHAO Yi. Abnormal changes in cerebral white matter fiber bundle in patients with retinal detachment[J]. Recent Advances in Ophthalmology, 2021, 0(6): 545-548. DOI: 10.13389/j.cnki.rao.2021.0113 |
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| Authors: | XU Yunfang LIANG Rongbin ZHANG Lijuan PAN Yicong GE Qianmin LI Qiuyu SHI Wenqing ZHOU Qiong SHAO Yi |
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| Affiliation: | Department of Opthalmology,the First Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi Province,China |
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| Abstract: | Objective To investigate the abnormal changes in white matter fiber tracts in patients with retinal detachment (RD) and the underlying pathophysiological mechanism of the disease through diffusion tensor imaging (DTI) data.Methods Thirty RD patients (16 males and 14 females) admitted in the Department of Ophthalmology of the First Affiliated Hospital of Nanchang University were selected as the observation group, and another 30 healthy individuals (16 males and 14 females) were recruited as the control group. The functional magnetic resonance imaging(MRI) data for all subjects were obtained from the eight-channel phased array head coil 3 Tesla MRI scanner. FMRIB software library was used to preprocess the MRI data which were analyzed by spatial statistics based on fiber bundle tracing. The tensor matrix was reconstructed by using v3.0 FMRIB toolbox according to the original data, and the anisotropic ratio of diffusion index was calculated. The anisotropic ratio of significant lesion area was analyzed statistically.Results There were no significant differences in age and body mass between the two groups (both P>0.05). The best corrected visions of the left and right eyes in the control group were better than those of the observation group, and the differences were statistically significant (both P<0.001). Compared with the control group, these data, including anisotropic ratio of the inferior fasciculus frontooccipitalis 1 (right), pars frontalis radiationis corporis callosi, inferior fasciculus frontooccipitalis 2 (right), the anterior corona radiata (left), superior longitudinal fasciculus (right), occipital radiation of corpus callosum and cingulate areas (right), were all increased significantly (all P<0.01).Conclusion The abnormal ratio of fiber bundle anisotropy in RD patients is related to the changes in visual function. |
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| Keywords: | retinal detachment diffusion tensor imaging spatial statistics based on fiber beam tracer |
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