上海市退休女干部乳腺微小癌影响因素的泊松回归分析及对应检测方法的诊断效能分析 |
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引用本文: | 史丽群,李照喜,师明莉,朱绘绘,闵贤,王美晨,黄璐,李文. 上海市退休女干部乳腺微小癌影响因素的泊松回归分析及对应检测方法的诊断效能分析[J]. 职业卫生与应急救援, 2021, 39(6): 631-636. DOI: 10.16369/j.oher.issn.1007-1326.2021.06.005 |
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作者姓名: | 史丽群 李照喜 师明莉 朱绘绘 闵贤 王美晨 黄璐 李文 |
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作者单位: | 华东疗养院物理诊断科,江苏 无锡 214000 |
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基金项目: | 上海市卫生和计划生育委员会科研课题计划任务20184Y0261 |
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摘 要: | 目的 探析上海市退休女干部乳腺微小癌患病情况、影响因素及对应检测方法的诊断效能,为后续诊断预防提供科学依据.方法 对2017年1月-2019年12月定期接受体检的12867例上海市退休女干部病历资料做回顾性分析.对体检对象先行乳腺查体及常规超声检查,检查为疑似乳腺微小癌患者再进行乳腺全容积成像(ABVS)联合数字钼靶(...
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关 键 词: | 退休女干部 乳腺微小癌 乳腺全容积成像 数字钼靶 影响因素 泊松回归 |
收稿时间: | 2021-02-10 |
Poisson regression analysis of influencing factors of minimal breast cancer in female retired cadres in Shanghai |
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Abstract: | Objective To analyze the prevalence status, influencing factors and diagnostic efficacy of corresponding detection methods of minimal breast cancer among female retired cadres in Shanghai, so as to provide scientific basis for follow-up diagnosis and prevention. Methods The medical records of 12 867 female retired cadres in Shanghai who underwent regular physical examination from December 2016 to December 2019 were analyzed retrospectively. These subjects were examined by breast physical examination and routine ultrasound, and the cases with suspected minimal breast cancer were examined by automated breast volume scanning(ABVS)combined with mammography(MG), and diagnosed by pathological method; Poisson regression was used to analyze the influencing factors of breast cancer. The consistency of the diagnostic results of each method was tested, and its diagnostic efficiency was analyzed. Results Totally 2 924 cases were detected as suspected minimal breast cancer in 12 867 female retired cadres, and 10 cases were diagnosed as minimal breast cancer by pathological methods. The detection rates of minimal breast cancer in 2017, 2018 and 2019 were 69.99/105, 74.74/105 and 87.59/105, respectively. The total physical examination rate was 77.72/105. Poisson regression analysis showed that age ≥ 50 years old, overweight and obesity, genetic history of breast related diseases, history of X-ray irradiation, occupational stress, failure to breastfeed, menopause, history of previous hormone use, history of thyroid disease, unmarried or widowed, and history of hysteromyoma were risk factors for minimal breast cancer(OR = 1.137 - 2.296, P < 0.05). The consistency Kappa values of three methods (ABVS, MG and ABVS + MG combination)and confirmed cases were 0.889, 0.823 and 1.000, respectively (P < 0.05);the sensitivity was > 0.700, the specificity was > 0.999, and the accuracy was > 0.999. Among 10 patients with minimal breast cancer, 8 cases were diagnosed by ABVS, and 2 cases were misdiagnosed as benign lesions; 7 cases were diagnosed by MG, and 3 cases were misdiagnosed as benign lesions. Conclusions There is a high prevalence of minimal breast cancer among female retired cadres in Shanghai, which is affected by many high-risk factors. ABVS combined with MG technology is recommended for routine screening, so as to provide reference for early diagnosis and treatment of breast cancer. |
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