| 高危人群结核分枝杆菌潜伏感染检测及预防性治疗专家共识 |
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| 引用本文： | 中国防痨协会. 高危人群结核分枝杆菌潜伏感染检测及预防性治疗专家共识[J]. 中国防痨杂志, 2021, 43(9): 874-878. DOI: 10.3969/j.issn.1000-6621.2021.09.004 |
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| 作者姓名： | 中国防痨协会 |
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| 基金项目： | “十三五”重大传染病防治国家科技重大专项(2020ZX09201001-005);“十三五”重大传染病防治国家科技重大专项(2018ZX10103001-001-008);“十三五”重大传染病防治国家科技重大专项(2017ZX10201301-001-003);“十二五”重大传染病防治国家科技重大专项(2014ZX10003001-004);“十二五”重大传染病防治国家科技重大专项(2015ZX09108-003) |
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| 摘 要： | 主动发现和预防性治疗是全球终结结核病流行策略下,结核病防治行动的重要举措。我国是全球结核病高负担国家之一,要实现全球终止结核病目标,加强结核分枝杆菌潜伏感染(latent tuberculosis infection,LTBI)者的主动发现,对结核病患者密切接触者进行筛查,对新近感染和免疫力低下LTBI人群给予预防性治疗,是降低LTBI者发病的重要措施。然而,当前业内人士对预防性治疗的适用对象、化学药物预防性治疗方案和预防性治疗效果尚存在较多疑虑和争议,同时,新的诊断技术和预防性治疗方法也在不断研究和应用。有鉴于此,中国防痨协会组织专家编写了《高危人群结核分枝杆菌潜伏感染检测及预防性治疗专家共识》,从LTBI检测原理,以及预防性治疗对象、诊断方法、化学预防和免疫预防等方面进行论述,以供我国结核病防治工作者借鉴和参考。
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| 关 键 词： | 分枝杆菌 结核 传染病潜伏期 诊断 预防和防护用药 总结性报告(主题) |
| 收稿时间： | 2021-07-27 |
Expert consensus on detection and preventive treatment of latent tuberculosis infection in high-risk population |
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| Chinese Antituberculosis Association. Expert consensus on detection and preventive treatment of latent tuberculosis infection in high-risk population[J]. The Journal of The Chinese Antituberculosis Association, 2021, 43(9): 874-878. DOI: 10.3969/j.issn.1000-6621.2021.09.004 |
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| Authors: | Chinese Antituberculosis Association |
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| Abstract: | Active discovery and preventive treatment is the core measure of tuberculosis control of the global strategy for ending tuberculosis epidemic. China is one of the countries with high burden of tuberculosis in the world. For the goal of ending tuberculosis in the world, strengthening the active discovery of latent tuberculosis infection (LTBI), screening the close contacts of tuberculosis patients, and preventive treatment for the newly infected and immunocompromised LTBI populations are important measures to reduce the incidence of LTBI. However, there are still many doubts and disputes about the applicable objects, regimes and effect of preventive treatment now. New diagnostic techniques and preventive treatment methods are constantly studied and applied. In view of this, experts from Chinese Antituberculosis Association have compiled the Expert consensus on detection and preventive treatment of latent tuberculosis infection in high-risk population, and reviewed the principle and detection of LTBI, and objects of prevention treatment, diagnostic methods, chemical prevention and immunization prevention, to provide reference for Chinese tuberculosis control workers. |
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| Keywords: | Mycobacterium tuberculosis Infectious disease incubation period Diagnosis Protective agents Consensus development conferences as topic |
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