| 双氯芬酸钠缓释胶囊与布洛芬缓释胶囊治疗类风湿性关节炎比较 |
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| 引用本文： | 任晓明. 双氯芬酸钠缓释胶囊与布洛芬缓释胶囊治疗类风湿性关节炎比较[J]. 医药导报, 2003, 22(12): 860-861 |
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| 作者姓名： | 任晓明 |
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| 作者单位： | 云南省昆明市延安医院药剂科,650051 |
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| 摘 要： | 目的:比较双氯芬酸钠缓释胶囊和布洛芬缓释胶囊治疗类风湿性关节炎的疗效及安全性.方法:采用随机分组的对照方法,将168例患者分为治疗组86例,口服双氯芬酸钠缓释胶囊50 mg,bid,对照组82例,口服布洛芬缓释胶囊300 mg,tid,均以2周为1个疗程.结果:两药均能显著改善类风湿性关节炎的症状,治疗组和对照组总有效率分别为76.74%,63.41%(P＞0.05),显效率分别为56.98%,37.80%(P＜0.05).不良反应均较轻.结论:双氯芬酸钠缓释胶囊对类风湿性关节炎的疗效优于布洛芬缓释胶囊.
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| 关 键 词： | 双氯芬酸钠 布洛芬 缓释胶囊 关节炎,类风湿性 |
| 文章编号： | 1004-0781(2003)12-0860-02 |
| 修稿时间： | 2002-12-19 |
A Contrasted Study of the Effect of Diclofenac Sodium Sustained Release Capsules and Ibuprofen Sustained Release Capsules in the Treatment of Rheumatoid Arthritis |
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| REN Xiao ming. A Contrasted Study of the Effect of Diclofenac Sodium Sustained Release Capsules and Ibuprofen Sustained Release Capsules in the Treatment of Rheumatoid Arthritis[J]. Herald of Medicine, 2003, 22(12): 860-861 |
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| Authors: | REN Xiao ming |
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| Abstract: | Objective:To make a contrasted study of the curative effect and safety rate of diclofenac sodium sustained release capsules and ibuprofen sustained release capsules in the treatment of rheumatoid arthritis(RA). Methods:168 patients with RA were randomly divided into two groups. Patients of the treatment group( n =86) were given each 50 mg of diclofenac sodium in sustained release capsules, PO b.i.d., while those of the control group ( n =82) were given each 300 mg of ibuprofen in sustained release capsules, PO b.i.d.. The course of treatment in both groups lasted 2 weeks. Patients of both groups were subjected to 2 courses of treatment. Results:Both diclofenac sodium sustained release capsules and ibuprofen sustained release capsules were shown to dramatically ameliorate the symptoms of RA at the termination of the treatment. The overall effective rates were 76.74% and 63.41% in the treatment group and control group, respectively ( P >0.05). However, the rates of excellent therapeutic effect were 56.98% and 37.80% in the treatment group and control group, respectively( P <0.05). Conclusion:The curative effect and safety rate of diclofenac sodium sustained release capsules were found to be better than those of ibuprofen sustained release capsules. |
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| Keywords: | Diclofenac sodium Ibuprofen Sustained release capsules Rheumatoid arthritis |
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