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New orally active DNA minor groove binding small molecule CT‐1 acts against breast cancer by targeting tumor DNA damage leading to p53‐dependent apoptosis |
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| Authors: | Karan Singh Saini Hamidullah Raghib Ashraf Dhanaraju Mandalapu Sharmistha Das Mohd Quadir Siddiqui Sonam Dwivedi Jayanta Sarkar Vishnu Lal Sharma Rituraj Konwar |
| Affiliation: | 1. Division of Endocrinology, CSIR‐Central Drug Research Institute, Lucknow, India;2. Division of Biochemistry, CSIR‐Central Drug Research Institute, Lucknow, India;3. Medicinal & Process Chemistry Division, CSIR‐Central Drug Research Institute, Lucknow, India;4. Advanced Centre for Treatment, Research and Education in Cancer, Kharghar, Navi Mumbai, Maharashtra, India;5. Academy of Scientific and Innovative Research (AcSIR), New Delhi, India |
| Abstract: | |
| Keywords: | breast cancer anti‐cancer cell cycle apoptosis curcumin mimic |