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| 胞外囊泡在皮肤科的研究进展和应用前景 | |
| 引用本文： | 陈伟 谢恒 李利. 胞外囊泡在皮肤科的研究进展和应用前景[J]. 中华皮肤科杂志, 2021, 54(10): 910-914. DOI: 10.35541/cjd.20191072 |
| 作者姓名： | 陈伟 谢恒 李利 |
| 作者单位： | 1成都市第二人民医院医疗美容科610017；2广东省皮肤病医院医学美容科，广州510095；3四川大学华西医院皮肤科，成都610041 |
| 摘 要： | 【摘要】 胞外囊泡是由细胞分泌的纳米级囊泡，包括外泌体和微囊泡。它可以通过多种机制被受体细胞摄取，传递细胞间信息，调控细胞的生物学功能。有研究发现，胞外囊泡与自身免疫性疾病、色素性疾病、肿瘤及皮肤创伤愈合等密切相关，在各种生理和病理过程中发挥着重要的生物学作用。本文综述胞外囊泡与皮肤科相关研究进展。 |
| 关 键 词： | 外泌体 胞外囊泡 微囊泡 皮肤疾病 |
| 收稿时间： | 2019-11-10 |
Extracellular vesicles in dermatology: updates and prospects |
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| Chen Wei,Xie Heng,Li Li. Extracellular vesicles in dermatology: updates and prospects[J]. Chinese Journal of Dermatology, 2021, 54(10): 910-914. DOI: 10.35541/cjd.20191072 | |
| Authors: | Chen Wei Xie Heng Li Li |
| Affiliation: | 1Department of Medical Cosmetology, Chengdu Second People′s Hospital, Chengdu 610017, China; 2 Department of Medical Cosmetology, Guangdong Provincial Dermatology Hospital, Guangzhou 510095, China; 3Department of Dermatology, West China Hospital, Sichuan University, Chengdu 610041, China |
| Abstract: | 【Abstract】 Extracellular vesicles are nanoscale vesicles secreted by cells, including exosomes and microvesicles. They can be ingested by recipient cells through a variety of mechanisms, transmitting intercellular information and regulating biological functions of recipient cells. Studies have found that extracellular vesicles are closely related to skin diseases, such as autoimmune diseases, pigmented diseases, tumors and wound healing, and play important biological roles in various physiological and pathological processes. This review summarizes updates on extracellular vesicles in dermatology. |
| Keywords: | Exosomes Extracellular vesicles Microvesicles Skin diseases |
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