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Detection of anti-neutrophil cytoplasmic antibodies after acute Plasmodium falciparum malaria.
Authors:C Wenisch   H Wenisch   H C Bankl   M Exner   W Graninger   S Looareesuwan     H Rumpold
Abstract:Four of 30 patients with Plasmodium falciparum infection in Bangkok, Thailand, were positive for anti-neutrophil cytoplasmic antibodies by indirect immunofluorescence 1 month after antimalarial therapy. No myeloperoxidase, proteinase 3, lactoferrin, or elastase reactivity was found. Since no evidence of vasculitis was seen in these patients, anti-neutrophil cytoplasmic antibody production in malaria-infected susceptible patients probably represents a secondary response, indicating neutrophil activation.
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