| 静脉用药不良反应与药液中不溶性微粒数量相关性的初步分析 |
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| 引用本文： | 汪艳,王桂芳,叶海英. 静脉用药不良反应与药液中不溶性微粒数量相关性的初步分析[J]. 南方医科大学学报, 2004, 24(1): 24-26 |
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| 作者姓名： | 汪艳 王桂芳 叶海英 |
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| 作者单位： | 第一军医大学珠江医院药剂科, 广东, 广州, 510282 |
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| 基金项目： | 广东省医学科研基金(A2003471)~~ |
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| 摘 要： | 目的 探讨静脉用药不良反应与有关不溶性微粒数量的相关性。方法 模拟临床输液配制操作过程,对本院临床常用药配伍,测定进入病人静脉前液体不溶性微粒的数量。结果 经输液器后不溶性微粒的数量均未超过中国药典中规定的相应标准。结论 本院绝大部分输液药物不良反应可排除由于中国药典规定的有关微粒数量超标而引起的可能性。
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| 关 键 词： | 静脉输液 不溶性微粒数量 药物不良反应 |
| 文章编号： | 1000-2588(2004)01-0024-03 |
| 修稿时间： | 2003-04-07 |
Analysis of the association between the quantity of insoluble particles in intravenously administered solution with adverse drug reactions |
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| WANG Yan,WANG Gui-fang,YE Hai-ying. Analysis of the association between the quantity of insoluble particles in intravenously administered solution with adverse drug reactions[J]. Journal of Southern Medical University, 2004, 24(1): 24-26 |
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| Authors: | WANG Yan WANG Gui-fang YE Hai-ying |
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| Affiliation: | WANG Yan,WANG Gui-fang,YE Hai-ying Department of Pharmacy,Zhujiang Hospital,First Military Medical University,Guangzhou 510282,China |
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| Abstract: | Objective To investigate th e possible association between adverse drug reactions and the quantity of insolu ble par-ticles in the intravenously administred drugs. Methods The solutions wer e prepared following the procedures in routine clini-cal practice, and the quant ity of insoluble particles in these solutions were measured before and after the solutions went through the transfusion apparatus. Results The quantity of inso luble particles measured after the solutions passed through the transfu-sion app aratus was consistent with the standard documented in Chinese Pharmacopoeia. Con clusion Adverse intravenous re-actions occurring in our hospital has no associat ion with excessive quantity of insoluble particles in the administered drugs. |
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| Keywords: | intravenous transfusion quantity infusible particles adverse drug reac tion |
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