Successful epilepsy surgery in frontal lobe epilepsy with startle seizures: a SEEG studyFrontal epilepsy with startle seizures |
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| Authors: | Ana Ciurea Irina Popa Mihai Dragos Maliia Nagy Csilla‐Johanna Andrei Barborica Cristian Donos Jean Ciurea Ioan Opris Ioana Mindruta |
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| Affiliation: | 1. Neurology, Neurovascular Diseases National Institute, Bucharest, Romania;2. Physics Department, University of Bucharest, Bucharest, Romania;3. Neurosurgery Department, Bagdasar‐Arseni Hospital, Bucharest, Romania;4. Neurology Department, University Emergency Hospital, Bucharest, Romania;5. FHC Inc, Bowdoin, ME, USA;6. Department of Physiology & Pharmacology, Wake Forest University Health Sciences, Winston‐Salem, NC, USA;7. Neurology Department, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania |
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| Abstract: | Pre‐surgical assessment and surgical management of frontal epilepsy with normal MRI is often challenging. We present a case of a 33‐year‐old, right‐handed, educated male. During childhood, his seizures presented with mandibular myoclonus and no particular trigger. As a young adult, he developed seizures with a startle component, triggered by unexpected noises. During his ictal episodes, he felt fear and grimaced with sudden head flexion and tonic axial posturing. Similar seizures also occurred without startle. Neuropsychological assessment showed executive dysfunction and verbal memory deficit. The cerebral MRI was normal. Electro‐clinical reasoning, investigations performed, the results obtained and follow‐up are discussed in detail. [Published with video sequence] |
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| Keywords: | startle epilepsy mesial fronto‐parietal network SEEG focal cortical dysplasia |
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