| 发热伴血小板减少综合征病毒动物感染及动物模型 |
| |
| 引用本文： | 孙娜,陈志海. 发热伴血小板减少综合征病毒动物感染及动物模型[J]. 实验动物与比较医学, 2017, 25(5): 577-580 |
| |
| 作者姓名： | 孙娜 陈志海 |
| |
| 作者单位： | 首都医科大学附属北京地坛医院,北京 100015,首都医科大学附属北京地坛医院,北京 100015 |
| |
| 基金项目： | 北京市医院管理局临床医学发展专项（No.XMLX201502，ZYLX201602） |
| |
| 摘 要： | 发热伴血小板减少综合征病毒（severe fever with thrombocytopenia syndrome virus，SFTSV）是我国2009年发现的一种新型布尼亚病毒。蜱虫是其重要储存宿主及传播媒介，野生动物和家畜均存在自然感染。α/β干扰素受体基因敲除的免疫缺陷小鼠是理想的实验动物模型。本文综述了SFTSV的动物感染及动物模型的研究成果，为SFTSV自然流行的控制以及动物实验提供依据。
|
| 关 键 词： | 发热伴血小板减少综合征病毒 蜱虫 动物感染 动物模型 |
| 收稿时间： | 2017-05-05 |
Research advances on animal infection and animal models of severe fever with thrombocytopenia syndrome virus |
| |
| SUN Na and CHEN Zhi-hai. Research advances on animal infection and animal models of severe fever with thrombocytopenia syndrome virus[J]. Laboratory Animal and Comparative Medicine, 2017, 25(5): 577-580 |
| |
| Authors: | SUN Na and CHEN Zhi-hai |
| |
| Affiliation: | Beijing Ditan Hospital Capital Medical University,Beijing 100015,China and Beijing Ditan Hospital Capital Medical University,Beijing 100015,China |
| |
| Abstract: | Severe fever with thrombocytopenia syndrome virus(SFTSV)is a novel Bunyavirus which was first reported in China in 2009. Tick is its important reservoir host and vector. Both wild and domestic animals can be naturally infected. IFNAR-/- immunodeficient mice are ideal experimental animal models. In this article, the research result of animal infection and animal models of SFTSV are summarized, which provide the basis for the control of SFTSV natural epidemic and for animal experiments. |
| |
| Keywords: | Sever fever with thrombocytopenia syndrome virus,SFTSV Tick Animal infection Animal model Disease control |
|
| 点击此处可从《实验动物与比较医学》浏览原始摘要信息 |
|
点击此处可从《实验动物与比较医学》下载免费的PDF全文 |
