| WHO乳腺肿瘤组织学新分类的特点问题与对策 |
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| 引用本文： | 于泳, 傅西林. WHO乳腺肿瘤组织学新分类的特点问题与对策[J]. 中国肿瘤临床, 2007, 34(23): 1373-1376. |
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| 作者姓名： | 于泳 傅西林 |
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| 作者单位： | 乳腺癌防治教育部重点实验室天津市肿瘤防治重点实验室天津医科大学附属肿瘤医院乳腺癌研究室, 天津市 300060 |
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| 摘 要： | WHO(2003)乳腺肿瘤组织学新分类较以往分类有许多优点:新分类体现了近代乳腺肿瘤病理学的最新进展,将新技术、新成果开始用于辅助诊断、分型及预测,并增加了一些新的肿瘤类型;重视与临床结合,增加术后病理分期和预后因素及预测因子,强调组织学分级和乳腺癌ER、PR及Her-2的表达与临床治疗及预后的意义;以人为本,体现人性化,提出导管上皮内瘤新概念,并将浸润性癌归为癌,导管内癌归入导管上皮内瘤,小叶原位癌归入小叶性肿瘤,对于疑似恶性病变要
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| 关 键 词： | 乳腺肿瘤 组织学分类 WHO |
| 收稿时间： | 2007-01-29 |
| 修稿时间： | 2007-01-29 |
WHO Classification of Breast Tumor Histology |
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| Yu Yong, Fu Xi-lin. WHO Classification of Breast Tumor Histology[J]. CHINESE JOURNAL OF CLINICAL ONCOLOGY, 2007, 34(23): 1373-1376. |
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| Authors: | Yu Yong Fu Xilin |
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| Affiliation: | Department of Breast Cancer Research, Tianjin Cancer Institute & Hospital, Tianjin |
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| Abstract: | The 2003 WHO classification of breast tumor histology represented the advances in breast tumor histology and new techniques used in diagnosis, histological typing and forecasting prognosis. Some new histological types were nominated. The new classification system emphasized the combination of clinic and pathology. pTNM stages and prognostic factors were also added. It mentioned the significance of histological grading and expression of ER, PR and Her- 2, and defined ductal intraep-ithelial neoplasia. Invasive carcinoma was relabeled carcinoma, and ductal carcinoma in situ was relabeled ductal intraepithelial neoplasia. Lobular carcinoma in situ was reclassified as lobular neoplasia.The diagnosis of suspicious malignant lesions should be downgraded to avoid the harm to patients' physical and mental state of overdiagnosis and overtreatment. The new classification system will act as a reference instead of an imperative. In spite of the merits above, deficiencies still existed, such as poor systematics and irrationality in grades and classifications of some tumors. Because some frequently seen lesions are not included in the new classification, pathologists may feel confused in the process of diagnosis. In clinical practice, we should combine the new classification with our practical experience to benefit patients. |
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| Keywords: | WHO |
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