| 超声睫状体成形术治疗难治性青光眼的临床效果及安全性 |
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| 引用本文： | 杨丛丛,姜涛,王大博. 超声睫状体成形术治疗难治性青光眼的临床效果及安全性[J]. 眼科新进展, 2018, 0(10): 982-985. DOI: 10.13389/j.cnki.rao.2018.0232 |
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| 作者姓名： | 杨丛丛 姜涛 王大博 |
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| 作者单位： | 266000 山东省青岛市，青岛大学附属医院眼科 |
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| 摘 要： | 目的 探讨超声睫状体成形术治疗难治性青光眼的临床效果及安全性。方法 收集我院确诊的20例20眼难治性青光眼患者，其中11例为闭角型青光眼，9例为外伤及糖尿病等其他疾病引起的继发性青光眼（或新生血管性青光眼），行超声睫状体成形术治疗。术后随访患者眼压、疼痛等级评分、眼表以及并发症发生情况。结果 术后1 d、1周、1个月、2个月及3个月闭角型青光眼患者以及继发性青光眼患者眼压均较术前下降，差异均有统计学意义（均为P＜0.05）。术后1 d、1周、1个月、2个月、3个月闭角型青光眼患者眼压降低率依次为25.91％、42.07％、51.66％、51.99％、64.15％，继发性青光眼患者依次为35.96％、45.66％、45.86％、50.30％、51.72％，两组患者术后较术前眼压均明显下降，但闭角型青光眼患者的降眼压效果更好。术后1 d、1周、1个月、2个月及3个月闭角型青光眼患者以及继发性青光眼患者疼痛等级评分均较术前下降，差异均有统计学意义（均为P＜0.05）。术后第1天17眼出现球结膜充血，2眼发生明显角膜水肿；术后第2天12眼出现球结膜充血，之前2眼角膜水肿明显减轻；术后1周球结膜未见明显充血，之前2眼角膜轻度水肿，术后1个月所有患者球结膜均无充血、角膜透明。术后第1天大部分患者眼痛较以前减轻，其中1眼疼痛与术前相同，之后给予药物止疼后症状缓解，术后1周疼痛感自行消失。结论 超声睫状体成形术治疗难治性青光眼安全性高，降眼压效果明显，可减轻患者眼部疼痛，改善眼部症状。
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| 关 键 词： | 超声睫状体成形术 高强度聚焦超声 难治性青光眼 眼压 |
Clinical effect and safety of ultrasond ciliary body plasty in the treatment of refractory glaucoma |
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| YANG Cong-Cong,JIANG Tao,WANG Da-Bo. Clinical effect and safety of ultrasond ciliary body plasty in the treatment of refractory glaucoma[J]. Recent Advances in Ophthalmology, 2018, 0(10): 982-985. DOI: 10.13389/j.cnki.rao.2018.0232 |
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| Authors: | YANG Cong-Cong JIANG Tao WANG Da-Bo |
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| Affiliation: | Department of Ophthalmology，Affiliated Hospital of Qingdao University，Qingdao 266000，Shandong Province，China |
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| Abstract: | Objective To investigate the clinical effect and safety of ultrasond ciliary body plasty in the treatment of refractory glaucoma.Methods Twenty patients with twenty eyes of refractory glaucoma diagnosed in our hospital were collected.Among them，eleven patients were angle-closure glaucoma and nine patients were secondary glaucoma （or neovascular glaucoma） caused by trauma，diabetes and other diseases，and were treated by ultrasond ciliary body plasty.Intraocular pressure （IOP），pain grade scores，ocular surface and complications after operation were followed up.Results Intraocular pressure in patients with angle-closure glaucoma and secondary glaucoma decreased on day 1，1 week，1 month，2 months and 3 months after operation and the differences were statistically significant （all P<0.05）.The decrease rate of IOP in patients with angle-closure glaucoma was 25.91％，42.07％，51.66％，51.99％and 64.15%，respectively and secondary glaucoma was 35.96％，45.66％，45.86％，50.30％ and 51.72％，respectively on day 1，1 week，1 month，2 months and 3 months after operation.The IOP in both groups was significantly lower than that before operation，but the effect of IOP was better in the patients with angle-closure glaucoma.The pain grade scores of patients with angle-closure glaucoma and secondary glaucoma were significantly lower than before operation on day 1，1 week，1 month，2 months and 3 months and the differences were statistically significant （all P<0.05）.Seventeen eyes appeared bulbar conjunctival hyperemia and two eyes appeared obvious corneal edema on the first day after operation.Twelve eyes appeared bulbar conjunctival hyperemia，and corneal edema was alleviated in the previous two eyes on day 2 after operation.There was no obvious hyperemia in the bulbar conjunctiva and mild corneal edema in the previous two eyes on 1 week after operation.There was no obvious hyperemia in the bulbar conjunctiva，and clear corneal were found in all patients on 1 month after operation.On day 1 after operation，eye pain in most of the patients was alleviated，and the pain in one eye was the same as that before operation，and the symptoms were relieved after the administration of medicine，and the feeling of pain disappeared on 1 week after the operation.Conclusion Ultrasond ciliary body plasty is a safe procedure，and has significant effect on reducing intraocular pressure，alleviating ocular pain and improving ocular symptoms in refractory glaucoma. |
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| Keywords: | ultrasound ciliary body plasty high intensity focused ultrasound refractory glaucoma intraocular pressure |
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