| 中国大陆人群对人乳头瘤病毒预防性疫苗的认知和态度 |
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| 引用本文： | 富诗岚,余艳琴,徐慧芳,胡尚英,乔友林,赵方辉. 中国大陆人群对人乳头瘤病毒预防性疫苗的认知和态度[J]. 中国肿瘤临床, 2018, 45(23): 1220-1224. DOI: 10.3969/j.issn.1000-8179.2018.23.172 |
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| 作者姓名： | 富诗岚 余艳琴 徐慧芳 胡尚英 乔友林 赵方辉 |
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| 作者单位： | 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院流行病学研究室（北京市100021） |
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| 基金项目： | 中国医学科学院医学与健康科技创新工程重大协同创新项目2016-I2M-1-019 |
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| 摘 要： | 目的 了解中国大陆人群对人乳头瘤病毒（human papillomavirus，HPV）预防性疫苗的认知和态度，并寻找可能的影响因素，为HPV疫苗在我国进一步推广应用提供参考依据。 方法 2009年5月至2012年5月在中国大陆，针对普通公众、医务人员和在校学生开展全国性大规模横断面流行病学调查研究，通过调查问卷收集研究对象的基本情况、对HPV疫苗的认知和态度等信息，采用χ2检验、Logistic回归方法进行统计学分析。 结果 研究共回收18 677份有效问卷，研究对象的中位年龄为32（15~79）岁。在疫苗认知方面，仅24.5%的研究对象曾听闻HPV预防性疫苗，14.1%知道HPV疫苗可预防宫颈癌等疾病。83.5%的受调查者表示愿意为自己、配偶或孩子接种疫苗，其中比较了解疫苗的人群、农村人群和女性人群对疫苗接种的态度更为积极（校正后OR值分别为2.81、2.14和1.25）。不愿接种HPV疫苗人群主要的担心是疫苗的安全性（占64.7%）。有关疫苗价格，66.3%的受调查者能够接受的最高定价低于300元。 结论 中国大陆人群对HPV疫苗认知度较低，但对疫苗接种普遍态度积极。应加强开展人群有关知识的健康教育，消除对HPV疫苗安全性等的顾虑，在接种疫苗时给予一定的优惠政策是必要的。
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| 关 键 词： | 子宫颈癌 人乳头瘤病毒 HPV疫苗 认知 |
| 收稿时间： | 2018-11-01 |
Knowledge and attitudes toward prophylactic human papillomavirus vaccines among the mainland Chinese population |
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| Affiliation: | Department of Epidemiology, National Cancer Center/National Clinical Research Center for Cancer and Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China |
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| Abstract: | Objective To assess knowledge of and attitudes toward prophylactic HPV vaccines among the mainland Chinese population and to determine possible influencing factors in order to provide reference data for policymakers to develop HPV vaccination strategies in China. Methods This large-scale national cross-sectional epidemiological study was conducted from May 2009 to May 2012. The general population, medical personnel, and school students participated in the investigation. Participants'basic information, as well as their knowledge of and attitudes toward HPV vaccines were collected through questionnaires. Chi-square tests and Logistic regression were performed for the statistical analysis. Results A total of 18, 677 people responded effectively, with a median age of 32 (ranging from 15 to 79 years). In terms of vaccine awareness, only 24.5% had heard of prophylactic HPV vaccines and 14.1% knew that HPV vaccines can prevent diseases such as cervical cancer. The good news was that 83.5% of respondents were willing to vaccinate themselves, their partners, or their children. People who knew more about vaccines, the rural population, and female participants were more likely to hold positive attitudes toward vaccination (adjusted ORs were 2.81, 2.14, and 1.25, respectively). Those participants who were reluctant to accept HPV vaccination were concerned mainly about the safety of the vaccines (64.7%). Furthermore, 66.3% of the respondents expected the maximum price of the HPV vaccine to be less than 300 RMB. Conclusions Mainland Chinese people generally know little about HPV vaccines. However, most of them think positively about the vaccinations after learning about them. It is high time for the government to launch HPV and cervical cancer health education or promotional campaigns to eliminate concerns about HPV vaccine safety. Furthermore, discounted or free vaccines are needed. |
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