| 正电子发射计算机断层显像-CT在肺结核活动性评价中的价值 |
| |
| 引用本文： | 李多,吕平欣. 正电子发射计算机断层显像-CT在肺结核活动性评价中的价值[J]. 中国防痨杂志, 2022, 44(4): 409-411. DOI: 10.19982/j.issn.1000-6621.20210712 |
| |
| 作者姓名： | 李多 吕平欣 |
| |
| 作者单位： | 1.首都医科大学附属北京友谊医院放射科,北京 100050;2.北京老年医院放射科,北京 100095 |
| |
| 摘 要： | 影像学一直是结核病活动性评价的重要方法之一,18F-氟代脱氧葡萄糖(18F-FDG)正电子发射计算机断层显像(PET)-CT能反映细胞的葡萄糖代谢程度,可以从代谢角度结合形态学层面综合评价结核病的活动性。18F-FDG PET-CT有可能识别出结核分枝杆菌潜伏感染者中处于亚临床状态的患者。陈旧性结核病灶无18F-FDG摄取的患者复发风险低。18F-FDG PET-CT能早期评估抗结核治疗效果,标准化摄取值(standard uptake value,SUV)降低表明治疗效果好,无18F-FDG摄取可能提示治疗达到了杀灭结核分枝杆菌的效果,18F-FDG PET-CT有望作为抗结核新药疗效评价及确定治疗时间截点的检查方法。本文中,笔者即对18F-FDG PET-CT识别结核分枝杆菌潜伏感染者,以及评价结核病患者抗结核治疗疗效、预后等方面的应用与价值进行综述。
|
| 关 键 词： | 诊断 体层摄影术 鉴别 结核 肺 综述 正电子发射断层显像术 发射型计算机 |
| 收稿时间： | 2021-12-21 |
Value of PET-CT in the evaluation of pulmonary tuberculosis activity |
| |
| LI Duo,LYU Ping-xin. Value of PET-CT in the evaluation of pulmonary tuberculosis activity[J]. The Journal of The Chinese Antituberculosis Association, 2022, 44(4): 409-411. DOI: 10.19982/j.issn.1000-6621.20210712 |
| |
| Authors: | LI Duo LYU Ping-xin |
| |
| Affiliation: | 1.Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China;2.Department of Radiology, Beijing Geriatric Hospital, Beijing 100095, China |
| |
| Abstract: | Imaging plays an important role in the evaluation of tuberculosis activity. 18F-fluorodeoxyglucose (18F-FDG) PET-CT provides both metabolic and morphology information of tuberculosis. 18F-FDG-PET-CT can indicate the degree of glucose metabolism of cells, which could be used to comprehensively evaluate the activity of tuberculosis combined with morphological features. 18F-FDG-PET-CT may identify subclinical pulmonary tuberculosis in patients with latent tuberculosis infection. Patients with obsolete pulmonary tuberculosis without 18F-FDG uptake have low risk of recurrence. 18F-FDG-PET-CT can early evaluate the effect of anti-tuberculosis treatment, the decrease of standard uptake value (SUV) indicates effective treatment, and no 18F-FDG uptake may indicate that the Mycobacterium tuberculosis have been killed because of the treatment. 18F-FDG PET-CT may be used as an examination method to evaluate the efficacy of new anti-tuberculosis drugs and determine the endpoint of treatment time. This paper reviews the application and value of 18F-FDG PET-CT in identifying latent tuberculosis infection and evaluating the efficacy and prognosis of anti-tuberculous therapy in tuberculosis patients. |
| |
| Keywords: | Positron-emission tomography Tomography emission-computed Tuberculosis pulmonary Diagnosis differential Review |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《中国防痨杂志》浏览原始摘要信息 |
|
点击此处可从《中国防痨杂志》下载全文 |
|
